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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMACR
All Species:
29.09
Human Site:
S369
Identified Species:
53.33
UniProt:
Q9UHK6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHK6
NP_055139.4
382
42360
S369
E
E
I
Y
Q
L
N
S
D
K
I
I
E
S
N
Chimpanzee
Pan troglodytes
XP_001152698
382
42384
S369
E
E
I
Y
Q
L
N
S
D
K
I
I
E
S
N
Rhesus Macaque
Macaca mulatta
XP_001088403
382
42109
S369
E
E
I
D
Q
L
K
S
D
K
I
I
E
S
N
Dog
Lupus familis
XP_855429
382
41810
S369
T
E
I
N
Q
L
T
S
D
K
I
I
E
I
N
Cat
Felis silvestris
Mouse
Mus musculus
O09174
381
41700
S368
E
E
I
L
Q
L
H
S
D
R
I
V
E
S
D
Rat
Rattus norvegicus
P70473
382
41810
S369
E
E
I
H
Q
L
H
S
D
R
I
I
E
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026619
383
41722
S370
E
E
I
A
K
L
Y
S
D
K
V
I
E
S
S
Frog
Xenopus laevis
NP_001167512
381
41146
T368
R
E
I
S
D
L
Q
T
C
G
A
V
A
R
N
Zebra Danio
Brachydanio rerio
NP_001018462
382
41394
S369
A
Q
I
E
Q
L
L
S
A
G
I
V
E
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610054
373
41594
L360
P
D
E
F
K
D
L
L
D
S
G
V
L
S
L
Honey Bee
Apis mellifera
XP_395802
380
42448
I366
H
E
E
I
T
N
F
I
A
N
G
I
V
N
Q
Nematode Worm
Caenorhab. elegans
Q09618
340
37713
V327
I
A
N
P
S
P
R
V
W
T
Q
D
E
L
A
Sea Urchin
Strong. purpuratus
XP_794568
384
41379
A371
K
E
V
K
E
M
C
A
S
G
V
A
E
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
92.6
80.6
N.A.
77.2
77.7
N.A.
N.A.
71.2
63.3
62.8
N.A.
49.7
49.7
38.7
54.9
Protein Similarity:
100
99.2
96.3
90.8
N.A.
88.2
89
N.A.
N.A.
85.9
79.5
81.1
N.A.
65.7
70.6
55.2
71.8
P-Site Identity:
100
100
86.6
73.3
N.A.
66.6
80
N.A.
N.A.
66.6
26.6
46.6
N.A.
13.3
13.3
6.6
13.3
P-Site Similarity:
100
100
86.6
73.3
N.A.
93.3
100
N.A.
N.A.
86.6
40
60
N.A.
40
20
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
0
8
16
0
8
8
8
0
16
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
8
0
% C
% Asp:
0
8
0
8
8
8
0
0
62
0
0
8
0
0
8
% D
% Glu:
47
77
16
8
8
0
0
0
0
0
0
0
77
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
24
16
0
0
0
0
% G
% His:
8
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
70
8
0
0
0
8
0
0
54
54
0
8
0
% I
% Lys:
8
0
0
8
16
0
8
0
0
39
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
70
16
8
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
8
0
8
16
0
0
8
0
0
0
8
54
% N
% Pro:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
54
0
8
0
0
0
8
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
8
0
0
16
0
0
0
8
0
% R
% Ser:
0
0
0
8
8
0
0
62
8
8
0
0
0
54
8
% S
% Thr:
8
0
0
0
8
0
8
8
0
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
8
0
0
16
31
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _