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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMACR All Species: 14.55
Human Site: S39 Identified Species: 26.67
UniProt: Q9UHK6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHK6 NP_055139.4 382 42360 S39 V R V D R P G S R Y D V S R L
Chimpanzee Pan troglodytes XP_001152698 382 42384 S39 V R V D R P G S R Y D V S R L
Rhesus Macaque Macaca mulatta XP_001088403 382 42109 S39 V R V E R P G S H Y D V S R L
Dog Lupus familis XP_855429 382 41810 A39 V R V D R L G A R G N M N I L
Cat Felis silvestris
Mouse Mus musculus O09174 381 41700 G38 V V R V N R L G S T G E N F L
Rat Rattus norvegicus P70473 382 41810 S39 V L V D R L G S V N H P S H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026619 383 41722 S40 R V D R A P R S A V A T D V Q
Frog Xenopus laevis NP_001167512 381 41146 S39 I R V D K A G S G T T M D T L
Zebra Danio Brachydanio rerio NP_001018462 382 41394 V39 I R V D R T K V A M T V D T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610054 373 41594 M38 V T R I D K V M E N P L D V L
Honey Bee Apis mellifera XP_395802 380 42448 F40 K V D K I D G F Y N T I D I L
Nematode Worm Caenorhab. elegans Q09618 340 37713 F29 C G M M L A D F G A D V T V I
Sea Urchin Strong. purpuratus XP_794568 384 41379 V42 D R I M Q M G V I S D T L S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 92.6 80.6 N.A. 77.2 77.7 N.A. N.A. 71.2 63.3 62.8 N.A. 49.7 49.7 38.7 54.9
Protein Similarity: 100 99.2 96.3 90.8 N.A. 88.2 89 N.A. N.A. 85.9 79.5 81.1 N.A. 65.7 70.6 55.2 71.8
P-Site Identity: 100 100 86.6 53.3 N.A. 13.3 53.3 N.A. N.A. 13.3 40 33.3 N.A. 13.3 13.3 13.3 20
P-Site Similarity: 100 100 93.3 80 N.A. 20 53.3 N.A. N.A. 13.3 60 40 N.A. 20 20 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 16 0 8 16 8 8 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 16 47 8 8 8 0 0 0 39 0 39 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 8 0 % F
% Gly: 0 8 0 0 0 0 62 8 16 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 8 0 0 8 0 % H
% Ile: 16 0 8 8 8 0 0 0 8 0 0 8 0 16 8 % I
% Lys: 8 0 0 8 8 8 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 8 16 8 0 0 0 0 8 8 0 70 % L
% Met: 0 0 8 16 0 8 0 8 0 8 0 16 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 24 8 0 16 0 0 % N
% Pro: 0 0 0 0 0 31 0 0 0 0 8 8 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 16 % Q
% Arg: 8 54 16 8 47 8 8 0 24 0 0 0 0 24 8 % R
% Ser: 0 0 0 0 0 0 0 47 8 8 0 0 31 8 0 % S
% Thr: 0 8 0 0 0 8 0 0 0 16 24 16 8 16 0 % T
% Val: 54 24 54 8 0 0 8 16 8 8 0 39 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 24 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _