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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMACR All Species: 34.55
Human Site: T198 Identified Species: 63.33
UniProt: Q9UHK6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHK6 NP_055139.4 382 42360 T198 L S S F L W K T Q K S S L W E
Chimpanzee Pan troglodytes XP_001152698 382 42384 T198 L S S F L W K T Q K S S L W E
Rhesus Macaque Macaca mulatta XP_001088403 382 42109 T198 L S S F L W K T Q K S S L W E
Dog Lupus familis XP_855429 382 41810 S198 L S S F L W H S L Q M G L W E
Cat Felis silvestris
Mouse Mus musculus O09174 381 41700 T197 L S S F L W K T Q P M G L W K
Rat Rattus norvegicus P70473 382 41810 T198 L S T F L W K T Q A M G L W A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026619 383 41722 S199 I S S F L W K S Q N L G L W N
Frog Xenopus laevis NP_001167512 381 41146 S197 L G S F V W K S Q K L G L W S
Zebra Danio Brachydanio rerio NP_001018462 382 41394 S198 V G S F M W K S R S I G L W N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610054 373 41594 S197 V A S W L F M S R N L V I W G
Honey Bee Apis mellifera XP_395802 380 42448 S197 I G S W M Y R S Q N I F G L W
Nematode Worm Caenorhab. elegans Q09618 340 37713 A162 F A G G G L S A A F G I L S A
Sea Urchin Strong. purpuratus XP_794568 384 41379 G199 V S S W L W M G R N M G L F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 92.6 80.6 N.A. 77.2 77.7 N.A. N.A. 71.2 63.3 62.8 N.A. 49.7 49.7 38.7 54.9
Protein Similarity: 100 99.2 96.3 90.8 N.A. 88.2 89 N.A. N.A. 85.9 79.5 81.1 N.A. 65.7 70.6 55.2 71.8
P-Site Identity: 100 100 100 60 N.A. 73.3 66.6 N.A. N.A. 60 60 40 N.A. 20 13.3 6.6 33.3
P-Site Similarity: 100 100 100 73.3 N.A. 80 73.3 N.A. N.A. 73.3 73.3 66.6 N.A. 66.6 53.3 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 0 0 0 8 8 8 0 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 % E
% Phe: 8 0 0 70 0 8 0 0 0 8 0 8 0 8 0 % F
% Gly: 0 24 8 8 8 0 0 8 0 0 8 54 8 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 0 0 0 0 0 16 8 8 0 0 % I
% Lys: 0 0 0 0 0 0 62 0 0 31 0 0 0 0 8 % K
% Leu: 54 0 0 0 70 8 0 0 8 0 24 0 85 8 0 % L
% Met: 0 0 0 0 16 0 16 0 0 0 31 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 31 0 0 0 0 16 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 62 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 24 0 0 0 0 0 0 % R
% Ser: 0 62 85 0 0 0 8 47 0 8 24 24 0 8 16 % S
% Thr: 0 0 8 0 0 0 0 39 0 0 0 0 0 0 0 % T
% Val: 24 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 24 0 77 0 0 0 0 0 0 0 77 8 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _