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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMACR
All Species:
22.73
Human Site:
T221
Identified Species:
41.67
UniProt:
Q9UHK6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHK6
NP_055139.4
382
42360
T221
D
G
G
A
P
F
Y
T
T
Y
R
T
A
D
G
Chimpanzee
Pan troglodytes
XP_001152698
382
42384
M221
D
G
G
A
P
F
Y
M
T
Y
R
T
A
D
G
Rhesus Macaque
Macaca mulatta
XP_001088403
382
42109
T221
D
G
G
A
P
F
Y
T
T
Y
R
T
A
D
G
Dog
Lupus familis
XP_855429
382
41810
T221
D
G
G
A
P
F
Y
T
T
Y
R
T
A
D
G
Cat
Felis silvestris
Mouse
Mus musculus
O09174
381
41700
T220
D
G
G
A
P
F
Y
T
T
Y
K
T
A
D
G
Rat
Rattus norvegicus
P70473
382
41810
T221
D
G
G
A
P
F
Y
T
T
Y
K
T
A
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026619
383
41722
E222
D
S
G
A
P
F
Y
E
T
Y
K
T
S
D
G
Frog
Xenopus laevis
NP_001167512
381
41146
S220
D
G
G
S
P
F
Y
S
T
Y
K
T
A
D
G
Zebra Danio
Brachydanio rerio
NP_001018462
382
41394
D221
D
S
G
A
P
F
Y
D
T
Y
R
T
S
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610054
373
41594
F217
N
L
V
D
G
G
S
F
F
Y
D
T
Y
E
T
Honey Bee
Apis mellifera
XP_395802
380
42448
D221
D
S
G
A
H
F
Y
D
T
Y
E
T
K
D
K
Nematode Worm
Caenorhab. elegans
Q09618
340
37713
L183
N
G
G
K
G
C
L
L
D
C
S
M
T
E
G
Sea Urchin
Strong. purpuratus
XP_794568
384
41379
E222
D
T
G
A
P
F
Y
E
T
Y
R
T
L
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
92.6
80.6
N.A.
77.2
77.7
N.A.
N.A.
71.2
63.3
62.8
N.A.
49.7
49.7
38.7
54.9
Protein Similarity:
100
99.2
96.3
90.8
N.A.
88.2
89
N.A.
N.A.
85.9
79.5
81.1
N.A.
65.7
70.6
55.2
71.8
P-Site Identity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
80
80
N.A.
13.3
60
20
80
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
86.6
100
86.6
N.A.
26.6
60
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
77
0
0
0
0
0
0
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
85
0
0
8
0
0
0
16
8
0
8
0
0
85
0
% D
% Glu:
0
0
0
0
0
0
0
16
0
0
8
0
0
16
0
% E
% Phe:
0
0
0
0
0
85
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
62
93
0
16
8
0
0
0
0
0
0
0
0
85
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
31
0
8
0
8
% K
% Leu:
0
8
0
0
0
0
8
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% R
% Ser:
0
24
0
8
0
0
8
8
0
0
8
0
16
0
0
% S
% Thr:
0
8
0
0
0
0
0
39
85
0
0
93
8
0
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
85
0
0
93
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _