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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX25
All Species:
28.48
Human Site:
S74
Identified Species:
44.76
UniProt:
Q9UHL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHL0
NP_037396.3
483
54692
S74
L
N
K
L
I
H
Q
S
L
V
E
S
S
H
R
Chimpanzee
Pan troglodytes
XP_001148850
483
54654
S74
L
N
K
L
I
H
Q
S
L
V
E
S
S
H
R
Rhesus Macaque
Macaca mulatta
XP_001112142
483
54710
S74
L
N
K
L
I
R
Q
S
L
V
E
S
S
H
R
Dog
Lupus familis
XP_536532
572
64423
S163
L
N
K
L
I
R
Q
S
L
V
E
S
S
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY15
484
54858
S75
L
N
K
L
I
R
Q
S
L
I
E
S
S
H
R
Rat
Rattus norvegicus
Q9QY16
483
54773
S74
L
N
K
L
I
R
Q
S
L
V
E
S
S
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507052
439
50084
K61
T
F
E
E
L
Q
L
K
Q
E
L
L
R
G
I
Chicken
Gallus gallus
NP_001006568
479
53883
T74
R
S
N
L
V
D
T
T
N
Q
V
E
V
L
Q
Frog
Xenopus laevis
Q9DGP9
483
54526
T74
L
N
K
L
L
R
R
T
L
V
D
S
P
H
N
Zebra Danio
Brachydanio rerio
NP_775365
487
54764
N77
L
N
K
L
I
R
S
N
L
V
N
T
T
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61305
460
51297
H70
K
N
P
N
S
P
L
H
S
V
K
T
F
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P27639
402
45389
N23
A
D
G
L
I
E
G
N
Y
D
Q
V
V
E
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93ZG7
496
55366
S75
I
L
E
E
P
E
D
S
N
I
K
A
V
T
S
Baker's Yeast
Sacchar. cerevisiae
P20449
482
53855
K74
I
S
S
E
Y
E
V
K
V
K
L
A
D
I
Q
Red Bread Mold
Neurospora crassa
Q8X0X2
483
53197
L70
Q
N
D
T
E
S
P
L
Y
S
V
S
S
F
D
Conservation
Percent
Protein Identity:
100
99.5
97.9
77.4
N.A.
92.9
93.5
N.A.
76.5
63.1
63.7
63.2
N.A.
53.6
N.A.
33.7
N.A.
Protein Similarity:
100
99.7
98.7
80.5
N.A.
96.2
96.4
N.A.
83.6
79.9
80.1
79.6
N.A.
68.9
N.A.
56.7
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
0
6.6
53.3
46.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
33.3
80
80
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
43.6
43
Protein Similarity:
N.A.
N.A.
N.A.
58.2
63.7
62.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
14
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
7
7
0
0
7
7
0
7
0
7
% D
% Glu:
0
0
14
20
7
20
0
0
0
7
40
7
0
14
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
7
0
0
0
7
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
14
0
7
0
0
0
0
0
47
0
% H
% Ile:
14
0
0
0
54
0
0
0
0
14
0
0
0
7
7
% I
% Lys:
7
0
54
0
0
0
0
14
0
7
14
0
0
0
0
% K
% Leu:
54
7
0
67
14
0
14
7
54
0
14
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
67
7
7
0
0
0
14
14
0
7
0
0
7
7
% N
% Pro:
0
0
7
0
7
7
7
0
0
0
0
0
7
0
0
% P
% Gln:
7
0
0
0
0
7
40
0
7
7
7
0
0
0
20
% Q
% Arg:
7
0
0
0
0
40
7
0
0
0
0
0
7
0
40
% R
% Ser:
0
14
7
0
7
7
7
47
7
7
0
54
47
0
14
% S
% Thr:
7
0
0
7
0
0
7
14
0
0
0
14
7
7
0
% T
% Val:
0
0
0
0
7
0
7
0
7
54
14
7
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
14
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _