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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX25
All Species:
47.88
Human Site:
Y428
Identified Species:
75.24
UniProt:
Q9UHL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHL0
NP_037396.3
483
54692
Y428
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Chimpanzee
Pan troglodytes
XP_001148850
483
54654
Y428
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Rhesus Macaque
Macaca mulatta
XP_001112142
483
54710
Y428
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Dog
Lupus familis
XP_536532
572
64423
Y517
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY15
484
54858
Y429
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Rat
Rattus norvegicus
Q9QY16
483
54773
Y428
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507052
439
50084
G392
L
H
R
I
G
R
T
G
R
F
G
K
K
G
L
Chicken
Gallus gallus
NP_001006568
479
53883
Y423
G
N
P
D
N
E
T
Y
L
H
R
I
G
R
T
Frog
Xenopus laevis
Q9DGP9
483
54526
Y428
G
S
V
D
F
E
T
Y
L
H
R
I
G
R
T
Zebra Danio
Brachydanio rerio
NP_775365
487
54764
Y431
G
N
P
D
N
E
T
Y
L
H
R
I
G
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61305
460
51297
Y404
G
M
A
D
C
E
T
Y
L
H
R
I
G
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P27639
402
45389
R355
N
R
E
N
Y
I
H
R
I
G
R
S
G
R
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93ZG7
496
55366
Y431
G
E
P
D
Y
E
V
Y
L
H
R
V
G
R
A
Baker's Yeast
Sacchar. cerevisiae
P20449
482
53855
Y420
G
Q
A
D
P
A
T
Y
I
H
R
I
G
R
T
Red Bread Mold
Neurospora crassa
Q8X0X2
483
53197
Y406
R
E
P
D
A
E
T
Y
L
H
R
I
G
R
T
Conservation
Percent
Protein Identity:
100
99.5
97.9
77.4
N.A.
92.9
93.5
N.A.
76.5
63.1
63.7
63.2
N.A.
53.6
N.A.
33.7
N.A.
Protein Similarity:
100
99.7
98.7
80.5
N.A.
96.2
96.4
N.A.
83.6
79.9
80.1
79.6
N.A.
68.9
N.A.
56.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
80
73.3
80
N.A.
73.3
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
80
80
80
N.A.
73.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
43.6
43
Protein Similarity:
N.A.
N.A.
N.A.
58.2
63.7
62.5
P-Site Identity:
N.A.
N.A.
N.A.
73.3
60
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
7
7
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
87
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
40
54
7
0
0
80
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
7
% F
% Gly:
40
0
0
0
7
0
0
7
0
7
7
0
94
7
0
% G
% His:
0
7
0
0
0
0
7
0
0
87
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
7
0
0
14
0
0
80
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% K
% Leu:
7
0
0
0
0
0
0
0
80
0
0
0
0
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
14
0
7
14
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
67
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
7
0
0
7
0
7
7
0
94
0
0
94
0
% R
% Ser:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
87
0
0
0
0
0
0
0
80
% T
% Val:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
54
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _