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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPN4
All Species:
19.7
Human Site:
S398
Identified Species:
43.33
UniProt:
Q9UHM6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHM6
NP_001025186.1
478
52635
S398
S
T
L
T
S
H
T
S
N
L
S
W
I
S
I
Chimpanzee
Pan troglodytes
XP_001135533
478
52629
S398
S
T
L
I
S
H
T
S
N
L
S
W
I
S
I
Rhesus Macaque
Macaca mulatta
XP_001088248
528
58258
S399
S
T
L
I
S
H
T
S
N
L
S
W
I
S
G
Dog
Lupus familis
XP_853735
561
60503
S419
S
T
L
S
S
Q
A
S
D
L
S
W
I
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXZ9
521
57213
S395
S
T
L
S
S
Q
S
S
D
L
S
W
I
S
G
Rat
Rattus norvegicus
Q8R456
474
52388
S395
S
T
L
S
S
Q
S
S
D
L
S
W
I
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001038118
528
58460
C453
E
H
S
A
T
S
T
C
K
T
S
E
K
C
N
Frog
Xenopus laevis
O57422
534
60325
E418
P
D
D
P
S
P
K
E
I
L
L
P
S
S
L
Zebra Danio
Brachydanio rerio
Q2KNE5
593
65510
G407
S
Q
S
S
D
M
S
G
R
F
R
R
T
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01668
369
41673
E300
I
N
Y
A
G
I
F
E
S
M
H
L
S
P
L
Honey Bee
Apis mellifera
Q17053
377
41998
I308
G
I
F
N
L
V
K
I
S
P
L
F
T
I
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
79.1
65.4
N.A.
70.6
77.1
N.A.
N.A.
53.4
40
47.3
N.A.
27.4
27.8
N.A.
N.A.
Protein Similarity:
100
99.7
81
71.4
N.A.
77.1
84.3
N.A.
N.A.
67.4
57.8
59.7
N.A.
43.5
47
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
66.6
N.A.
66.6
66.6
N.A.
N.A.
13.3
20
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
80
N.A.
86.6
86.6
N.A.
N.A.
20
26.6
26.6
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% C
% Asp:
0
10
10
0
10
0
0
0
28
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
19
0
0
0
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
10
0
10
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
37
% G
% His:
0
10
0
0
0
28
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
10
0
19
0
10
0
10
10
0
0
0
55
10
19
% I
% Lys:
0
0
0
0
0
0
19
0
10
0
0
0
10
0
0
% K
% Leu:
0
0
55
0
10
0
0
0
0
64
19
10
0
0
19
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
28
0
0
0
0
0
10
% N
% Pro:
10
0
0
10
0
10
0
0
0
10
0
10
0
10
0
% P
% Gln:
0
10
0
0
0
28
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
10
0
0
0
% R
% Ser:
64
0
19
37
64
10
28
55
19
0
64
0
19
73
0
% S
% Thr:
0
55
0
10
10
0
37
0
0
10
0
0
19
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
10
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _