KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NARF
All Species:
40.61
Human Site:
S431
Identified Species:
68.72
UniProt:
Q9UHQ1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHQ1
NP_001033707.1
456
51156
S431
E
W
L
E
G
I
N
S
P
K
A
R
E
V
L
Chimpanzee
Pan troglodytes
XP_511766
480
52717
S455
E
W
L
E
G
I
N
S
P
K
A
R
E
V
L
Rhesus Macaque
Macaca mulatta
XP_001113522
457
51273
S432
E
W
L
E
G
I
N
S
P
K
A
R
E
V
L
Dog
Lupus familis
XP_537935
473
52786
S448
E
W
L
D
G
A
D
S
P
R
A
Q
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYQ7
462
51797
S437
E
W
L
E
G
T
E
S
P
K
V
Q
E
V
L
Rat
Rattus norvegicus
Q2YDU6
456
51447
S431
E
W
L
E
G
T
E
S
P
K
V
Q
E
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513248
469
52242
S444
D
W
L
Q
G
T
D
S
P
K
V
Q
A
A
L
Chicken
Gallus gallus
XP_415606
781
86162
S756
D
W
L
E
G
M
D
S
R
K
V
Q
E
T
L
Frog
Xenopus laevis
Q6GP25
456
51492
S431
D
W
L
Q
G
A
E
S
Q
K
T
K
Q
T
L
Zebra Danio
Brachydanio rerio
Q6DHP6
465
52360
S437
D
W
L
D
G
H
D
S
P
H
A
Q
Q
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SYS7
477
54516
S451
D
F
L
D
G
F
Q
S
D
K
S
Y
D
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N392
457
50805
V425
D
E
E
T
W
I
K
V
R
E
E
W
E
K
L
Sea Urchin
Strong. purpuratus
XP_001191432
475
53102
S450
E
W
L
G
G
V
G
S
E
K
A
R
T
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGW5
581
62269
E499
E
W
Q
K
E
V
D
E
A
Y
F
S
G
D
E
Conservation
Percent
Protein Identity:
100
81
96.7
80.5
N.A.
84.8
86.4
N.A.
65.8
42.8
61.6
53.7
N.A.
37.3
N.A.
30.2
44.2
Protein Similarity:
100
84.3
98
87.7
N.A.
90.2
91.8
N.A.
78.2
50.7
80.4
73.7
N.A.
57.8
N.A.
50.3
63.1
P-Site Identity:
100
100
100
60
N.A.
73.3
73.3
N.A.
46.6
53.3
40
46.6
N.A.
40
N.A.
20
60
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
73.3
80
66.6
80
N.A.
73.3
N.A.
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
8
0
43
0
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
0
0
22
0
0
36
0
8
0
0
0
8
8
0
% D
% Glu:
58
8
8
43
8
0
22
8
8
8
8
0
58
0
8
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
86
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
29
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
72
0
8
0
8
0
% K
% Leu:
0
0
86
0
0
0
0
0
0
0
0
0
0
0
93
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% P
% Gln:
0
0
8
15
0
0
8
0
8
0
0
43
15
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
8
0
29
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
86
0
0
8
8
0
8
0
% S
% Thr:
0
0
0
8
0
22
0
0
0
0
8
0
8
15
0
% T
% Val:
0
0
0
0
0
15
0
8
0
0
29
0
0
43
0
% V
% Trp:
0
86
0
0
8
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _