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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NARF All Species: 10
Human Site: T449 Identified Species: 16.92
UniProt: Q9UHQ1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHQ1 NP_001033707.1 456 51156 T449 Y Q S Q E R G T H S L D I K W
Chimpanzee Pan troglodytes XP_511766 480 52717 A473 Y Q S Q E R G A H S L D I K W
Rhesus Macaque Macaca mulatta XP_001113522 457 51273 A450 Y Q S Q E R G A H S L D I K W
Dog Lupus familis XP_537935 473 52786 A466 Y Q G P G L P A L S R D I K W
Cat Felis silvestris
Mouse Mus musculus Q9CYQ7 462 51797 T455 Y Q S L E P C T D G L D I K W
Rat Rattus norvegicus Q2YDU6 456 51447 T449 Y Q S L E P C T D S L D I K W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513248 469 52242 A462 Y G A A E P P A P G P H I K W
Chicken Gallus gallus XP_415606 781 86162 A774 Y S A V N Q T A S N L D I K W
Frog Xenopus laevis Q6GP25 456 51492 A449 I V A S A Q S A A R L D M K W
Zebra Danio Brachydanio rerio Q6DHP6 465 52360 P455 Y K D H T H L P A H I T N P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8SYS7 477 54516 L469 Y H D V V S E L S I S L N I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N392 457 50805 D443 Y R N L L F T D Y R P V E T N
Sea Urchin Strong. purpuratus XP_001191432 475 53102 T468 Y H A L E K N T N A L N I K W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGW5 581 62269 D517 R A Q D E S L D L V V D G I S
Conservation
Percent
Protein Identity: 100 81 96.7 80.5 N.A. 84.8 86.4 N.A. 65.8 42.8 61.6 53.7 N.A. 37.3 N.A. 30.2 44.2
Protein Similarity: 100 84.3 98 87.7 N.A. 90.2 91.8 N.A. 78.2 50.7 80.4 73.7 N.A. 57.8 N.A. 50.3 63.1
P-Site Identity: 100 93.3 93.3 46.6 N.A. 66.6 73.3 N.A. 33.3 40 26.6 6.6 N.A. 6.6 N.A. 6.6 46.6
P-Site Similarity: 100 93.3 93.3 46.6 N.A. 66.6 73.3 N.A. 40 60 46.6 20 N.A. 6.6 N.A. 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29.6
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 44.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 29 8 8 0 0 43 15 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 8 0 0 0 15 15 0 0 65 0 0 8 % D
% Glu: 0 0 0 0 58 0 8 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 8 0 22 0 0 15 0 0 8 0 0 % G
% His: 0 15 0 8 0 8 0 0 22 8 0 8 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 8 0 65 15 0 % I
% Lys: 0 8 0 0 0 8 0 0 0 0 0 0 0 72 0 % K
% Leu: 0 0 0 29 8 8 15 8 15 0 58 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 8 0 8 0 8 8 0 8 15 0 15 % N
% Pro: 0 0 0 8 0 22 15 8 8 0 15 0 0 8 0 % P
% Gln: 0 43 8 22 0 15 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 0 22 0 0 0 15 8 0 0 0 0 % R
% Ser: 0 8 36 8 0 15 8 0 15 36 8 0 0 0 8 % S
% Thr: 0 0 0 0 8 0 15 29 0 0 0 8 0 8 0 % T
% Val: 0 8 0 15 8 0 0 0 0 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % W
% Tyr: 86 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _