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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R1 All Species: 29.39
Human Site: S169 Identified Species: 53.89
UniProt: Q9UHQ9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHQ9 NP_057327.2 305 34095 S169 N I Q P N K K S P P E P R V A
Chimpanzee Pan troglodytes XP_001141761 363 40501 S227 N I Q P N K K S P P E P R V A
Rhesus Macaque Macaca mulatta XP_001105252 305 34086 S169 N I Q P N K K S P P E P R V A
Dog Lupus familis XP_848311 305 33925 S169 N I Q P N K K S P P E P Q V A
Cat Felis silvestris
Mouse Mus musculus Q9DB73 305 34116 S169 N I Q P N K K S P P E L R V A
Rat Rattus norvegicus Q5EB81 305 34204 S169 N I Q P N K K S P P E L R V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518224 300 33346 T170 K S P A E P R T A K K L G M I
Chicken Gallus gallus Q5ZHX7 304 33589 A170 K P D K K S E A Q R K F A K H
Frog Xenopus laevis Q5PQA4 296 32646 H169 P K I K V A K H V G M L A G G
Zebra Danio Brachydanio rerio Q0P487 309 34369 S173 A I R P D K K S E A E V R K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623086 308 34610 D172 S V K I L R K D P P T E Y N V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194747 350 39037 S214 S I K A D K K S A P K K K F A
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 H486 V I N G K Q R H A S R L A M I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 99.3 90.8 N.A. 91.8 91.1 N.A. 82.6 61.3 60 55.3 N.A. N.A. 54.5 N.A. 52
Protein Similarity: 100 84 99.6 96.7 N.A. 97 95.7 N.A. 90.8 77 78.3 74.1 N.A. N.A. 74 N.A. 69.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 0 6.6 46.6 N.A. N.A. 20 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 26.6 20 6.6 60 N.A. N.A. 46.6 N.A. 73.3
Percent
Protein Identity: N.A. 23.6 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 34.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 16 0 8 0 8 24 8 0 0 24 0 54 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 16 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 8 0 8 0 54 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % F
% Gly: 0 0 0 8 0 0 0 0 0 8 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 8 % H
% Ile: 0 70 8 8 0 0 0 0 0 0 0 0 0 0 16 % I
% Lys: 16 8 16 16 16 62 77 0 0 8 24 8 8 16 0 % K
% Leu: 0 0 0 0 8 0 0 0 0 0 0 39 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 16 0 % M
% Asn: 47 0 8 0 47 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 8 8 8 54 0 8 0 0 54 62 0 31 0 0 0 % P
% Gln: 0 0 47 0 0 8 0 0 8 0 0 0 8 0 0 % Q
% Arg: 0 0 8 0 0 8 16 0 0 8 8 0 47 0 0 % R
% Ser: 16 8 0 0 0 8 0 62 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % T
% Val: 8 8 0 0 8 0 0 0 8 0 0 8 0 47 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _