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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R1 All Species: 40
Human Site: Y252 Identified Species: 73.33
UniProt: Q9UHQ9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHQ9 NP_057327.2 305 34095 Y252 H P P K D W A Y S K G F V T A
Chimpanzee Pan troglodytes XP_001141761 363 40501 Y310 H P P K D W A Y S K G F V T A
Rhesus Macaque Macaca mulatta XP_001105252 305 34086 Y252 H P P K D W A Y S K G F V T A
Dog Lupus familis XP_848311 305 33925 Y252 H P P E D W A Y S K G F V T A
Cat Felis silvestris
Mouse Mus musculus Q9DB73 305 34116 Y252 S P P E D W T Y S K G F V T A
Rat Rattus norvegicus Q5EB81 305 34204 Y252 Y P P E D W T Y S K G F V T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518224 300 33346 Y247 Q P P K G W S Y G R G F V T A
Chicken Gallus gallus Q5ZHX7 304 33589 Y251 R P P Q D W K Y S S G F V T A
Frog Xenopus laevis Q5PQA4 296 32646 V266 P P S E D V L V L M C G P P P
Zebra Danio Brachydanio rerio Q0P487 309 34369 Y256 R P S E G W K Y S E G F V N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623086 308 34610 Y255 T S S E N W Q Y S T G H I N A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194747 350 39037 Y297 R P G E G W Q Y S S G F V S E
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 Y567 R P E E G W K Y S V G F V T E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 99.3 90.8 N.A. 91.8 91.1 N.A. 82.6 61.3 60 55.3 N.A. N.A. 54.5 N.A. 52
Protein Similarity: 100 84 99.6 96.7 N.A. 97 95.7 N.A. 90.8 77 78.3 74.1 N.A. N.A. 74 N.A. 69.4
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. 66.6 73.3 13.3 53.3 N.A. N.A. 33.3 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 80 80 20 66.6 N.A. N.A. 53.3 N.A. 60
Percent
Protein Identity: N.A. 23.6 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 34.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 60 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 31 0 0 0 0 0 0 0 77 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 62 0 0 0 0 0 8 0 0 0 0 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 85 0 0 0 % F
% Gly: 0 0 8 0 31 0 0 0 8 0 93 8 0 0 0 % G
% His: 31 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 31 0 0 24 0 0 47 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 16 0 % N
% Pro: 8 93 62 0 0 0 0 0 0 0 0 0 8 8 8 % P
% Gln: 8 0 0 8 0 0 16 0 0 0 0 0 0 0 0 % Q
% Arg: 31 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 8 24 0 0 0 8 0 85 16 0 0 0 8 0 % S
% Thr: 8 0 0 0 0 0 16 0 0 8 0 0 0 70 0 % T
% Val: 0 0 0 0 0 8 0 8 0 8 0 0 85 0 0 % V
% Trp: 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _