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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 20
Human Site: S1630 Identified Species: 36.67
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 S1630 G I P T D G D S H A V T Y P P
Chimpanzee Pan troglodytes XP_001138050 2188 240763 S1644 G I P T D G D S H A V T Y P P
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 S1630 G I P T D G D S H A I T Y P P
Dog Lupus familis XP_537704 2182 240593 S1638 G I P T D G D S H A I T Y P P
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 A1629 P T D G D S H A I T Y P P A I
Rat Rattus norvegicus NP_001100505 2040 223488 S1523 E N K D E S T S S S N V W T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 D1626 V G V P T D G D S H A I T Y P
Chicken Gallus gallus XP_415884 2225 244861 S1681 G V P T D G D S H A I T Y P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 D1573 V G V P T D G D S H A V T Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 G2072 L G D P L G M G E T L E D I N
Honey Bee Apis mellifera XP_393643 1982 216109 I1465 I N S M P E N I R S N I N V Q
Nematode Worm Caenorhab. elegans Q93442 2862 325119 N2327 V G M E G M D N V A K P I P D
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 S610 A E E E G E V S V A T L G L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 93.3 93.3 N.A. 6.6 6.6 N.A. 6.6 86.6 N.A. 6.6 N.A. 6.6 0 20 13.3
P-Site Similarity: 100 100 100 100 N.A. 13.3 26.6 N.A. 6.6 100 N.A. 6.6 N.A. 13.3 13.3 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 8 0 54 16 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 8 47 16 47 16 0 0 0 0 8 0 8 % D
% Glu: 8 8 8 16 8 16 0 0 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 39 31 0 8 16 47 16 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 8 0 39 16 0 0 0 0 0 % H
% Ile: 8 31 0 0 0 0 0 8 8 0 24 16 8 8 8 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 8 0 0 0 8 0 0 0 0 0 8 8 0 8 8 % L
% Met: 0 0 8 8 0 8 8 0 0 0 0 0 0 0 8 % M
% Asn: 0 16 0 0 0 0 8 8 0 0 16 0 8 0 8 % N
% Pro: 8 0 39 24 8 0 0 0 0 0 0 16 8 47 54 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 16 0 54 24 16 0 0 0 0 0 % S
% Thr: 0 8 0 39 16 0 8 0 0 16 8 39 16 8 0 % T
% Val: 24 8 16 0 0 0 8 0 16 0 16 16 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 39 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _