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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 27.58
Human Site: S769 Identified Species: 50.56
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 S769 H A R P P S T S L I Y D S D L
Chimpanzee Pan troglodytes XP_001138050 2188 240763 S783 H A R P P S T S L I Y D S D L
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 S769 H A R P P S T S L I Y D S D L
Dog Lupus familis XP_537704 2182 240593 S778 H A R P P S T S L I Y D S D L
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 S768 H A R P P S T S L I Y D S D L
Rat Rattus norvegicus NP_001100505 2040 223488 K667 D E L T P G S K K S A S G S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 S766 H A R P P S T S L I Y D S D L
Chicken Gallus gallus XP_415884 2225 244861 S820 H A R T A S T S L I H E T D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 D710 P Y A F E E G D E E F N F S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 S1013 K R S T A V A S A A V A A A A
Honey Bee Apis mellifera XP_393643 1982 216109 E609 Q S Q T P K I E I K Q E P N V
Nematode Worm Caenorhab. elegans Q93442 2862 325119 S932 K N E K A G F S E K A I P S G
Sea Urchin Strong. purpuratus XP_001203054 1127 123639
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 100 66.6 N.A. 0 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 86.6 N.A. 13.3 N.A. 13.3 46.6 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 8 0 24 0 8 0 8 8 16 8 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 8 0 0 0 47 0 54 16 % D
% Glu: 0 8 8 0 8 8 0 8 16 8 0 16 0 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 8 0 8 0 0 % F
% Gly: 0 0 0 0 0 16 8 0 0 0 0 0 8 0 8 % G
% His: 54 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 54 0 8 0 0 0 % I
% Lys: 16 0 0 8 0 8 0 8 8 16 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 54 0 0 0 0 0 54 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 8 0 0 47 62 0 0 0 0 0 0 0 16 0 0 % P
% Gln: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 8 54 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 8 0 0 54 8 70 0 8 0 8 47 24 0 % S
% Thr: 0 0 0 31 0 0 54 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 47 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _