KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
27.58
Human Site:
S769
Identified Species:
50.56
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S769
H
A
R
P
P
S
T
S
L
I
Y
D
S
D
L
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S783
H
A
R
P
P
S
T
S
L
I
Y
D
S
D
L
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S769
H
A
R
P
P
S
T
S
L
I
Y
D
S
D
L
Dog
Lupus familis
XP_537704
2182
240593
S778
H
A
R
P
P
S
T
S
L
I
Y
D
S
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S768
H
A
R
P
P
S
T
S
L
I
Y
D
S
D
L
Rat
Rattus norvegicus
NP_001100505
2040
223488
K667
D
E
L
T
P
G
S
K
K
S
A
S
G
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S766
H
A
R
P
P
S
T
S
L
I
Y
D
S
D
L
Chicken
Gallus gallus
XP_415884
2225
244861
S820
H
A
R
T
A
S
T
S
L
I
H
E
T
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
D710
P
Y
A
F
E
E
G
D
E
E
F
N
F
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
S1013
K
R
S
T
A
V
A
S
A
A
V
A
A
A
A
Honey Bee
Apis mellifera
XP_393643
1982
216109
E609
Q
S
Q
T
P
K
I
E
I
K
Q
E
P
N
V
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
S932
K
N
E
K
A
G
F
S
E
K
A
I
P
S
G
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
66.6
N.A.
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
86.6
N.A.
13.3
N.A.
13.3
46.6
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
8
0
24
0
8
0
8
8
16
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
0
47
0
54
16
% D
% Glu:
0
8
8
0
8
8
0
8
16
8
0
16
0
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
16
8
0
0
0
0
0
8
0
8
% G
% His:
54
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
54
0
8
0
0
0
% I
% Lys:
16
0
0
8
0
8
0
8
8
16
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
54
0
0
0
0
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
8
0
0
47
62
0
0
0
0
0
0
0
16
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
54
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
54
8
70
0
8
0
8
47
24
0
% S
% Thr:
0
0
0
31
0
0
54
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
47
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _