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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
27.27
Human Site:
T1774
Identified Species:
50
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
T1774
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
T1788
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
T1774
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Dog
Lupus familis
XP_537704
2182
240593
T1782
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
L1773
V
K
D
K
Q
T
E
L
G
E
T
F
G
E
A
Rat
Rattus norvegicus
NP_001100505
2040
223488
R1667
Y
C
L
S
H
D
Q
R
W
I
L
A
S
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
T1770
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Chicken
Gallus gallus
XP_415884
2225
244861
T1825
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
T1717
A
P
V
K
D
K
Q
T
E
L
G
E
T
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
R2216
V
L
A
P
M
H
E
R
N
D
K
T
D
F
S
Honey Bee
Apis mellifera
XP_393643
1982
216109
D1609
E
T
A
T
I
N
I
D
I
P
N
R
K
R
R
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
M2471
P
P
P
M
V
Y
Q
M
D
E
K
G
K
A
I
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
G754
V
S
C
T
D
S
K
G
E
L
M
E
T
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
100
100
N.A.
100
N.A.
6.6
0
13.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
26.6
N.A.
100
100
N.A.
100
N.A.
13.3
0
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
16
0
0
0
0
0
0
0
0
8
0
8
8
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
62
8
0
8
8
8
0
0
8
0
0
% D
% Glu:
8
0
0
0
0
0
16
0
62
16
0
62
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
62
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
54
8
8
0
54
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
8
8
0
0
0
0
16
% I
% Lys:
0
8
0
62
0
54
8
0
0
0
16
0
16
0
0
% K
% Leu:
0
8
8
0
0
0
0
8
0
62
8
0
0
0
0
% L
% Met:
0
0
0
8
8
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
62
8
8
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
70
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
0
8
0
8
8
% R
% Ser:
0
8
0
8
0
8
0
0
0
0
0
0
8
0
8
% S
% Thr:
0
8
0
16
0
8
0
54
0
0
8
8
62
0
8
% T
% Val:
24
0
54
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _