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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 30.61
Human Site: T836 Identified Species: 56.11
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 T836 D L H K M Y P T P P S L E Q H
Chimpanzee Pan troglodytes XP_001138050 2188 240763 T850 D L H K M Y P T P P S L E Q H
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 T836 D L H K M Y P T P P S L E Q H
Dog Lupus familis XP_537704 2182 240593 T845 D L H K M Y P T P P S L E Q H
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 T835 D L H K M Y P T P P S L E Q H
Rat Rattus norvegicus NP_001100505 2040 223488 G734 S M D P T P G G T V L E G S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 T833 D L H K M Y P T P P S L E P H
Chicken Gallus gallus XP_415884 2225 244861 T887 D L H K M Y P T P P S L E Q H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 S777 D L D N L F N S D E D D L T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 T1080 I T S S I T T T C N T T I T S
Honey Bee Apis mellifera XP_393643 1982 216109 D676 K D L D Q I F D N S D P D T S
Nematode Worm Caenorhab. elegans Q93442 2862 325119 T999 N E L P M E V T S I G H I R T
Sea Urchin Strong. purpuratus XP_001203054 1127 123639
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 93.3 100 N.A. 13.3 N.A. 6.6 0 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 93.3 100 N.A. 33.3 N.A. 20 6.6 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 62 8 16 8 0 0 0 8 8 0 16 8 8 0 0 % D
% Glu: 0 8 0 0 0 8 0 0 0 8 0 8 54 0 0 % E
% Phe: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 8 0 0 8 0 8 0 0 % G
% His: 0 0 54 0 0 0 0 0 0 0 0 8 0 0 54 % H
% Ile: 8 0 0 0 8 8 0 0 0 8 0 0 16 0 0 % I
% Lys: 8 0 0 54 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 62 16 0 8 0 0 0 0 0 8 54 8 0 0 % L
% Met: 0 8 0 0 62 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 8 0 8 8 0 0 0 0 0 % N
% Pro: 0 0 0 16 0 8 54 0 54 54 0 8 0 8 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 47 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 0 8 8 0 0 0 8 8 8 54 0 0 8 24 % S
% Thr: 0 8 0 0 8 8 8 70 8 0 8 8 0 24 8 % T
% Val: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 54 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _