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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPN3
All Species:
39.7
Human Site:
Y254
Identified Species:
72.78
UniProt:
Q9UHW5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHW5
NP_057385.3
284
32761
Y254
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Chimpanzee
Pan troglodytes
XP_001142177
457
51859
Y427
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Rhesus Macaque
Macaca mulatta
XP_001107255
284
32775
Y254
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Dog
Lupus familis
XP_534673
284
32641
Y254
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3W4
284
32772
Y254
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Rat
Rattus norvegicus
Q6R518
284
32784
Y254
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505757
243
28291
G214
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
E
Chicken
Gallus gallus
XP_425270
284
32659
Y254
H
I
D
T
T
I
Q
Y
G
E
D
L
E
F
K
Frog
Xenopus laevis
Q4V7Z0
285
33039
Y254
H
I
D
F
A
I
Q
Y
G
E
D
L
E
F
K
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
Y254
H
I
D
F
S
I
Q
Y
G
E
D
L
E
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625026
281
32211
Y253
T
I
D
N
I
I
Q
Y
G
E
D
A
D
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788313
329
37053
Q256
N
L
Q
Y
D
E
D
Q
D
V
K
I
P
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06543
272
30635
T244
N
N
P
D
S
I
E
T
I
L
S
Y
V
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
99.3
97.8
N.A.
94.7
96.1
N.A.
76
86.6
84.9
83.8
N.A.
N.A.
56.6
N.A.
55.9
Protein Similarity:
100
62.1
100
98.5
N.A.
98.5
98.2
N.A.
82
94.7
93.3
93.6
N.A.
N.A.
74.3
N.A.
69.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
100
86.6
N.A.
N.A.
60
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
100
93.3
N.A.
N.A.
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
54
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
77
8
8
0
8
0
8
8
77
0
8
8
16
% D
% Glu:
0
0
0
0
0
8
8
0
8
77
0
8
70
0
8
% E
% Phe:
0
0
8
62
0
0
0
0
0
0
0
0
8
62
0
% F
% Gly:
0
0
0
0
0
0
0
8
77
0
0
0
0
0
0
% G
% His:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
77
0
0
16
85
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
77
% K
% Leu:
0
8
0
0
0
0
0
0
0
8
8
70
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
8
77
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
16
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
8
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
77
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _