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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A6
All Species:
19.39
Human Site:
T752
Identified Species:
47.41
UniProt:
Q9UHW9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHW9
NP_005126.1
1150
127617
T752
L
E
E
G
P
P
H
T
K
N
W
R
P
Q
L
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
T752
L
E
E
G
P
P
H
T
K
N
W
R
P
Q
L
Rhesus Macaque
Macaca mulatta
XP_001086105
1210
134182
T812
L
E
E
G
P
P
H
T
K
N
W
R
P
Q
L
Dog
Lupus familis
XP_848522
1151
127738
T753
L
E
E
G
P
P
H
T
K
N
W
R
P
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q924N4
1150
127478
T752
L
E
E
G
P
P
H
T
K
N
W
R
P
Q
L
Rat
Rattus norvegicus
Q63632
1085
120609
T725
L
K
A
G
K
G
L
T
I
V
G
S
V
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505237
1093
121937
L732
Q
L
K
A
G
K
G
L
T
I
I
G
S
V
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q0VGW6
899
98326
R552
R
T
S
S
Q
L
I
R
F
V
N
D
L
K
K
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
Q552
S
N
P
R
S
S
C
Q
L
I
C
F
V
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
D673
G
S
V
D
S
Q
K
D
K
N
R
A
R
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
93.1
98.6
N.A.
98
73
N.A.
73.7
N.A.
24.2
24.6
N.A.
N.A.
N.A.
34.5
N.A.
Protein Similarity:
100
100
93.8
99.3
N.A.
99.2
83.4
N.A.
83.7
N.A.
41.5
41.8
N.A.
N.A.
N.A.
52.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
13.3
N.A.
6.6
0
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
0
0
10
0
10
0
% D
% Glu:
0
50
50
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
10
0
0
60
10
10
10
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
20
10
0
0
10
10
% I
% Lys:
0
10
10
0
10
10
10
0
60
0
0
0
0
10
10
% K
% Leu:
60
10
0
0
0
10
10
10
10
0
0
0
10
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
60
10
0
0
10
0
% N
% Pro:
0
0
10
0
50
50
0
0
0
0
0
0
50
0
0
% P
% Gln:
10
0
0
0
10
10
0
10
0
0
0
0
0
50
20
% Q
% Arg:
10
0
0
10
0
0
0
10
0
0
10
50
10
0
0
% R
% Ser:
10
10
10
10
20
10
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
60
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
20
0
0
20
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _