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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PUF60 All Species: 26.06
Human Site: S41 Identified Species: 44.1
UniProt: Q9UHX1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHX1 NP_001129505.1 559 59875 S41 K P P Q G T D S I K M E N G Q
Chimpanzee Pan troglodytes XP_528257 640 68531 S122 K P P Q G T D S I K M E N G Q
Rhesus Macaque Macaca mulatta XP_001087975 560 59928 S42 K P P Q G T D S I K M E N G Q
Dog Lupus familis XP_856919 535 57780 T36 K L G L P P L T P E Q Q E A L
Cat Felis silvestris
Mouse Mus musculus Q3UEB3 564 60230 S46 K P P Q G T E S I K M E N G Q
Rat Rattus norvegicus XP_001071005 563 60102 S45 K P P Q G T E S I K M E N G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511498 531 58636 S44 W M P K G T D S I K M E N G Q
Chicken Gallus gallus NP_001026551 366 38878
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6IQE0 516 55402 E33 K A K K Y A M E Q S I K S V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T6B9 637 67921 I40 G K S T D S K I P Y L S Q P L
Honey Bee Apis mellifera XP_001121000 541 59288 L35 A G P G A K Y L T L P G I L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785572 595 63329 S38 S T P P P P P S L Q S F E F Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42698 387 42300
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 S88 S Q I G S V A S I R V C R D A
Conservation
Percent
Protein Identity: 100 86.7 99.8 94.9 N.A. 97.8 97.8 N.A. 76.5 63.1 N.A. 68.3 N.A. 45.8 54.3 N.A. 53.2
Protein Similarity: 100 87 99.8 95.1 N.A. 98.2 98.2 N.A. 80.6 64.4 N.A. 76.2 N.A. 58.2 68.6 N.A. 65.7
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 80 0 N.A. 6.6 N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 86.6 0 N.A. 33.3 N.A. 13.3 6.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. 20
Protein Similarity: N.A. N.A. N.A. 39.3 N.A. 36.6
P-Site Identity: N.A. N.A. N.A. 0 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 0 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 8 8 8 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 8 0 29 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 15 8 0 8 0 43 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % F
% Gly: 8 8 8 15 43 0 0 0 0 0 0 8 0 43 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 50 0 8 0 8 0 0 % I
% Lys: 50 8 8 15 0 8 8 0 0 43 0 8 0 0 0 % K
% Leu: 0 8 0 8 0 0 8 8 8 8 8 0 0 8 22 % L
% Met: 0 8 0 0 0 0 8 0 0 0 43 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 0 % N
% Pro: 0 36 58 8 15 15 8 0 15 0 8 0 0 8 0 % P
% Gln: 0 8 0 36 0 0 0 0 8 8 8 8 8 0 50 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 15 0 8 0 8 8 0 58 0 8 8 8 8 0 0 % S
% Thr: 0 8 0 8 0 43 0 8 8 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 8 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 8 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _