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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUF60
All Species:
21.82
Human Site:
S435
Identified Species:
36.92
UniProt:
Q9UHX1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHX1
NP_001129505.1
559
59875
S435
S
E
R
P
E
M
L
S
E
Q
E
H
M
S
I
Chimpanzee
Pan troglodytes
XP_528257
640
68531
S516
S
E
R
P
E
M
L
S
E
Q
E
H
M
S
I
Rhesus Macaque
Macaca mulatta
XP_001087975
560
59928
S436
S
E
R
P
E
M
L
S
E
Q
E
H
M
S
I
Dog
Lupus familis
XP_856919
535
57780
I418
S
E
Q
E
H
M
S
I
S
G
S
S
A
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3UEB3
564
60230
S440
S
E
R
P
E
M
L
S
E
Q
E
H
M
S
I
Rat
Rattus norvegicus
XP_001071005
563
60102
S439
S
E
R
P
E
M
L
S
E
Q
E
H
M
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511498
531
58636
K426
A
R
H
M
V
M
Q
K
L
L
R
K
Q
E
S
Chicken
Gallus gallus
NP_001026551
366
38878
P263
V
G
K
A
V
T
P
P
M
P
L
L
T
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6IQE0
516
55402
A413
A
S
A
G
R
Q
A
A
I
Q
S
K
S
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T6B9
637
67921
Q510
E
G
D
V
Q
T
L
Q
Q
Q
E
N
M
S
I
Honey Bee
Apis mellifera
XP_001121000
541
59288
Q416
E
T
E
P
Q
T
L
Q
Q
Q
E
N
M
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785572
595
63329
S471
V
E
L
P
Q
T
I
S
E
Q
E
N
M
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42698
387
42300
V284
I
N
G
E
P
T
R
V
L
L
L
R
N
M
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S6N6
764
82299
G586
G
Q
V
G
A
L
G
G
G
R
G
G
P
A
G
Conservation
Percent
Protein Identity:
100
86.7
99.8
94.9
N.A.
97.8
97.8
N.A.
76.5
63.1
N.A.
68.3
N.A.
45.8
54.3
N.A.
53.2
Protein Similarity:
100
87
99.8
95.1
N.A.
98.2
98.2
N.A.
80.6
64.4
N.A.
76.2
N.A.
58.2
68.6
N.A.
65.7
P-Site Identity:
100
100
100
20
N.A.
100
100
N.A.
6.6
0
N.A.
6.6
N.A.
40
46.6
N.A.
53.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
13.3
6.6
N.A.
33.3
N.A.
60
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
39.3
N.A.
36.6
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
8
0
8
8
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
15
50
8
15
36
0
0
0
43
0
58
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
15
8
15
0
0
8
8
8
8
8
8
0
0
8
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
36
0
0
8
% H
% Ile:
8
0
0
0
0
0
8
8
8
0
0
0
0
0
58
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
15
0
0
0
% K
% Leu:
0
0
8
0
0
8
50
0
15
15
15
8
0
0
0
% L
% Met:
0
0
0
8
0
50
0
0
8
0
0
0
58
8
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
22
8
0
0
% N
% Pro:
0
0
0
50
8
0
8
8
0
8
0
0
8
8
0
% P
% Gln:
0
8
8
0
22
8
8
15
15
65
0
0
8
0
0
% Q
% Arg:
0
8
36
0
8
0
8
0
0
8
8
8
0
8
0
% R
% Ser:
43
8
0
0
0
0
8
43
8
0
15
8
8
50
8
% S
% Thr:
0
8
0
0
0
36
0
0
0
0
0
0
8
15
0
% T
% Val:
15
0
8
8
15
0
0
8
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _