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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUF60
All Species:
25.15
Human Site:
Y274
Identified Species:
42.56
UniProt:
Q9UHX1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHX1
NP_001129505.1
559
59875
Y274
K
G
Y
G
F
I
E
Y
E
K
A
Q
S
S
Q
Chimpanzee
Pan troglodytes
XP_528257
640
68531
Y355
K
G
Y
G
F
I
E
Y
E
K
A
Q
S
S
Q
Rhesus Macaque
Macaca mulatta
XP_001087975
560
59928
Y275
K
G
Y
G
F
I
E
Y
E
K
A
Q
S
S
Q
Dog
Lupus familis
XP_856919
535
57780
S262
S
S
Q
D
A
V
S
S
M
N
L
F
D
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UEB3
564
60230
Y279
K
G
Y
G
F
I
E
Y
E
K
A
Q
S
S
Q
Rat
Rattus norvegicus
XP_001071005
563
60102
Y278
K
G
Y
G
F
I
E
Y
E
K
A
Q
S
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511498
531
58636
H269
R
D
P
T
T
G
K
H
K
G
T
D
S
S
V
Chicken
Gallus gallus
NP_001026551
366
38878
A107
D
T
I
R
Q
A
F
A
P
F
G
P
I
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6IQE0
516
55402
G257
G
G
Q
Y
L
R
V
G
K
A
V
T
P
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T6B9
637
67921
Y275
K
G
Y
G
F
I
E
Y
A
N
K
Q
A
M
D
Honey Bee
Apis mellifera
XP_001121000
541
59288
S259
A
A
L
E
A
I
A
S
M
N
L
F
D
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785572
595
63329
Y277
K
G
H
G
I
I
E
Y
D
S
M
Q
S
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42698
387
42300
R128
A
T
E
A
E
M
K
R
E
M
D
K
R
R
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S6N6
764
82299
K392
E
E
K
D
E
K
D
K
E
N
K
K
E
G
E
Conservation
Percent
Protein Identity:
100
86.7
99.8
94.9
N.A.
97.8
97.8
N.A.
76.5
63.1
N.A.
68.3
N.A.
45.8
54.3
N.A.
53.2
Protein Similarity:
100
87
99.8
95.1
N.A.
98.2
98.2
N.A.
80.6
64.4
N.A.
76.2
N.A.
58.2
68.6
N.A.
65.7
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
13.3
0
N.A.
6.6
N.A.
60
6.6
N.A.
53.3
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
40
0
N.A.
13.3
N.A.
66.6
6.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
39.3
N.A.
36.6
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
8
15
8
8
8
8
8
36
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
15
0
0
8
0
8
0
8
8
15
0
8
% D
% Glu:
8
8
8
8
15
0
50
0
50
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
43
0
8
0
0
8
0
15
0
0
0
% F
% Gly:
8
58
0
50
0
8
0
8
0
8
8
0
0
8
15
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
58
0
0
0
0
0
0
8
0
0
% I
% Lys:
50
0
8
0
0
8
15
8
15
36
15
15
0
8
0
% K
% Leu:
0
0
8
0
8
0
0
0
0
0
15
0
0
15
0
% L
% Met:
0
0
0
0
0
8
0
0
15
8
8
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
0
8
8
8
0
% P
% Gln:
0
0
15
0
8
0
0
0
0
0
0
50
0
0
43
% Q
% Arg:
8
0
0
8
0
8
0
8
0
0
0
0
8
8
0
% R
% Ser:
8
8
0
0
0
0
8
15
0
8
0
0
50
43
15
% S
% Thr:
0
15
0
8
8
0
0
0
0
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
43
8
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _