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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRBP1 All Species: 39.39
Human Site: S422 Identified Species: 78.79
UniProt: Q9UHY1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHY1 NP_037524.1 535 59845 S422 P Q Q E E V T S P V V P P S V
Chimpanzee Pan troglodytes XP_515359 671 74193 S558 P Q Q E E V T S P V V P P S V
Rhesus Macaque Macaca mulatta XP_001096971 543 60811 S430 P Q Q E E V T S P V V P P S V
Dog Lupus familis XP_532911 723 81196 S610 P Q Q E E V T S P V V P P S V
Cat Felis silvestris
Mouse Mus musculus Q99J45 535 59847 S422 P Q Q E E V T S P V V P P S V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508259 534 59466 S421 P Q Q E K V T S P V V P P S V
Chicken Gallus gallus NP_001006420 532 59674 S421 P Q Q V V V K S P I A P P S V
Frog Xenopus laevis NP_001084664 526 59348 S415 P Q Q E V V K S P V V P P S V
Zebra Danio Brachydanio rerio NP_001038654 535 60170 S425 P Q Q E A V K S P I V P P S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0Y6 637 70489 S473 N F R S R A A S P E R A D S V
Honey Bee Apis mellifera XP_623819 574 64921 S394 P V R P R A I S P E V T E S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9STK6 516 58930 S409 A V Q K C L S S P E T L H L D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.7 98.5 73.8 N.A. 98.3 N.A. N.A. 91.4 87.6 86.1 82.6 N.A. 45.2 55 N.A. N.A.
Protein Similarity: 100 79.7 98.5 73.8 N.A. 99.2 N.A. N.A. 94.5 91.7 91.9 89.5 N.A. 60.7 66.7 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 66.6 86.6 80 N.A. 26.6 40 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 73.3 86.6 86.6 N.A. 33.3 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 17 9 0 0 0 9 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % D
% Glu: 0 0 0 67 42 0 0 0 0 25 0 0 9 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 17 0 0 0 0 0 % I
% Lys: 0 0 0 9 9 0 25 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 84 0 0 9 0 0 0 0 100 0 0 75 75 0 0 % P
% Gln: 0 75 84 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 17 0 17 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 9 0 0 9 100 0 0 0 0 0 92 0 % S
% Thr: 0 0 0 0 0 0 50 0 0 0 9 9 0 0 0 % T
% Val: 0 17 0 9 17 75 0 0 0 59 75 0 0 0 92 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _