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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENOPH1
All Species:
46.06
Human Site:
Y193
Identified Species:
72.38
UniProt:
Q9UHY7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHY7
NP_067027.1
261
28933
Y193
H
K
V
E
S
E
S
Y
R
K
I
A
D
S
I
Chimpanzee
Pan troglodytes
XP_001142974
234
26107
Y166
H
K
V
E
S
E
S
Y
R
K
I
A
D
S
I
Rhesus Macaque
Macaca mulatta
XP_001094685
261
28836
Y193
R
K
V
E
S
E
S
Y
R
K
T
A
D
S
I
Dog
Lupus familis
XP_535629
297
33157
Y229
H
K
V
E
S
E
S
Y
R
K
I
A
N
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGB7
257
28582
Y190
H
K
V
D
S
E
S
Y
R
K
I
A
D
S
I
Rat
Rattus norvegicus
Q5PPH0
261
28856
Y190
H
K
V
E
S
D
S
Y
R
K
I
A
D
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512733
383
41345
Y233
S
K
V
E
S
E
S
Y
K
K
I
A
T
S
I
Chicken
Gallus gallus
XP_420559
308
33879
Y240
P
K
V
E
S
E
S
Y
R
R
I
A
A
S
I
Frog
Xenopus laevis
Q569R5
235
26828
L171
F
S
I
E
G
N
L
L
K
L
L
D
G
H
F
Zebra Danio
Brachydanio rerio
Q6GMI7
261
29959
Y193
A
K
V
E
S
K
S
Y
E
N
I
A
E
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN95
256
28279
Y182
H
K
Q
E
Q
Q
S
Y
K
N
I
A
K
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21012
248
27936
Y185
L
K
G
E
S
N
S
Y
T
K
I
S
E
R
I
Sea Urchin
Strong. purpuratus
XP_794501
282
31802
Y205
A
K
V
E
K
D
S
Y
T
Q
I
A
E
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B4G0F3
517
56952
Y456
N
K
R
E
T
R
S
Y
F
E
I
S
Q
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SBS7
234
26103
E169
K
Q
E
K
A
S
Y
E
K
I
A
A
K
H
Q
Conservation
Percent
Protein Identity:
100
89.6
98.4
79.8
N.A.
93.4
93
N.A.
34.7
66.5
58.6
61.6
N.A.
40.2
N.A.
41.3
50.3
Protein Similarity:
100
89.6
98.8
83.1
N.A.
96.5
96.5
N.A.
45.1
76.9
73.9
76.6
N.A.
58.6
N.A.
58.6
63.8
P-Site Identity:
100
100
86.6
93.3
N.A.
93.3
93.3
N.A.
80
80
6.6
60
N.A.
46.6
N.A.
53.3
46.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
86.6
86.6
26.6
73.3
N.A.
66.6
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
24.5
N.A.
N.A.
N.A.
39.4
Protein Similarity:
N.A.
34.8
N.A.
N.A.
N.A.
53.6
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
7
0
0
0
0
0
7
80
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
14
0
0
0
0
0
7
34
7
0
% D
% Glu:
0
0
7
87
0
47
0
7
7
7
0
0
20
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
7
0
0
0
0
0
0
0
7
0
0
% G
% His:
40
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
7
80
0
0
0
67
% I
% Lys:
7
87
0
7
7
7
0
0
27
54
0
0
14
0
0
% K
% Leu:
7
0
0
0
0
0
7
7
0
7
7
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
14
0
0
0
14
0
0
7
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
7
0
7
7
0
0
0
7
0
0
7
7
7
% Q
% Arg:
7
0
7
0
0
7
0
0
47
7
0
0
0
14
0
% R
% Ser:
7
7
0
0
67
7
87
0
0
0
0
14
0
60
0
% S
% Thr:
0
0
0
0
7
0
0
0
14
0
7
0
7
0
0
% T
% Val:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _