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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEZ2
All Species:
8.79
Human Site:
S59
Identified Species:
19.33
UniProt:
Q9UHY8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHY8
NP_005093.2
353
39666
S59
C
S
L
E
E
K
L
S
L
C
F
R
P
S
D
Chimpanzee
Pan troglodytes
XP_515402
355
39825
C61
M
S
E
Q
S
L
I
C
I
Y
S
S
S
P
L
Rhesus Macaque
Macaca mulatta
XP_001107258
382
42541
S61
C
S
L
E
E
K
L
S
L
C
F
R
P
S
D
Dog
Lupus familis
XP_863161
349
39183
S55
C
S
L
E
E
K
L
S
L
C
F
R
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6TYB5
348
39082
L54
A
S
S
L
E
E
K
L
S
L
C
F
R
P
T
Rat
Rattus norvegicus
P97578
375
42067
L54
A
S
S
L
E
E
K
L
S
L
C
F
R
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508140
305
35085
L19
R
E
R
I
W
N
A
L
T
D
N
Y
G
H
V
Chicken
Gallus gallus
XP_419521
731
82364
F47
G
A
K
L
S
L
X
F
E
P
P
P
A
R
A
Frog
Xenopus laevis
NP_001085822
392
45514
N70
N
E
F
D
E
K
L
N
V
C
F
R
N
Y
N
Zebra Danio
Brachydanio rerio
NP_001070900
339
38648
A49
S
L
D
E
T
L
S
A
S
F
P
Y
S
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392877
389
43746
I90
V
N
T
F
D
E
K
I
T
S
C
F
R
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
90.5
94.6
N.A.
89.5
85
N.A.
71.3
37.3
43.8
56
N.A.
N.A.
38.5
N.A.
N.A.
Protein Similarity:
100
92.1
90.8
96
N.A.
93.4
87.7
N.A.
75.6
40.4
59.4
72.2
N.A.
N.A.
58.3
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
13.3
13.3
N.A.
0
0
40
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
20
20
N.A.
0
6.6
66.6
13.3
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
0
10
10
0
0
0
0
10
0
10
% A
% Cys:
28
0
0
0
0
0
0
10
0
37
28
0
0
10
0
% C
% Asp:
0
0
10
10
10
0
0
0
0
10
0
0
0
10
19
% D
% Glu:
0
19
10
37
55
28
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
0
0
10
0
10
37
28
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
0
0
10
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
37
28
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
28
28
0
28
37
28
28
19
0
0
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
10
0
10
0
0
10
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
19
10
28
28
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
37
28
10
0
% R
% Ser:
10
55
19
0
19
0
10
28
28
10
10
10
19
28
10
% S
% Thr:
0
0
10
0
10
0
0
0
19
0
0
0
0
0
19
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
19
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _