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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EVL All Species: 26.97
Human Site: S219 Identified Species: 65.93
UniProt: Q9UI08 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI08 NP_057421.1 416 44620 S219 G S S H D E S S M S G L A A A
Chimpanzee Pan troglodytes XP_001153142 726 79409 S389 G S S H D E S S M S G L A A A
Rhesus Macaque Macaca mulatta XP_001104614 418 44787 S221 G S S H D E S S M S G L A A A
Dog Lupus familis XP_537553 419 44781 S222 G A S H D E S S V S G L A A A
Cat Felis silvestris
Mouse Mus musculus P70429 414 44319 S217 G T N H D E S S A S G L A A A
Rat Rattus norvegicus O08719 393 42076 S217 G T N H D E S S A S G L A A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516812 128 14537
Chicken Gallus gallus NP_001006487 418 44712 S220 G A A S E D G S V S G L A A A
Frog Xenopus laevis Q64GL0 692 73902 P519 G V V Y E E S P A S G L A A A
Zebra Danio Brachydanio rerio NP_991196 376 40801 Y217 P P L P V G G Y G A H G S A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.9 99.2 94.9 N.A. 93.9 88.9 N.A. 27.3 83.4 39.8 66.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 56.7 99.5 98 N.A. 97.3 92 N.A. 28.1 89 47.2 75.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 0 53.3 60 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 86.6 73.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 10 0 0 0 0 0 30 10 0 0 80 90 80 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 60 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 20 70 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 80 0 0 0 0 10 20 0 10 0 80 10 0 0 0 % G
% His: 0 0 0 60 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 0 80 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % M
% Asn: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 0 10 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 30 40 10 0 0 70 70 0 80 0 0 10 0 0 % S
% Thr: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 10 0 10 0 0 0 20 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _