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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1H
All Species:
22.42
Human Site:
S174
Identified Species:
41.11
UniProt:
Q9UI12
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI12
NP_057025.2
483
55883
S174
W
I
K
T
Q
L
S
S
Q
K
L
R
G
S
G
Chimpanzee
Pan troglodytes
XP_001150191
483
55912
S174
W
I
K
T
Q
L
S
S
Q
K
L
R
G
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544082
483
55817
S174
W
I
K
T
Q
L
S
S
Q
K
L
R
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVE3
483
55836
S174
W
I
K
T
Q
L
S
S
Q
K
L
R
G
S
G
Rat
Rattus norvegicus
NP_001013951
441
50841
L161
E
L
M
E
G
S
D
L
N
Y
Y
F
N
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515210
483
55883
S174
W
I
K
S
Q
L
S
S
Q
K
L
R
G
S
G
Chicken
Gallus gallus
XP_423862
445
52062
W164
D
L
N
Y
Y
F
N
W
I
K
T
Q
L
S
S
Frog
Xenopus laevis
NP_001089309
479
55249
S170
W
I
K
T
Q
L
S
S
Q
K
L
R
G
G
V
Zebra Danio
Brachydanio rerio
NP_775377
463
53422
W163
D
L
N
Y
Y
F
N
W
I
K
T
Q
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J1
468
53715
F164
D
L
N
F
Y
L
Q
F
L
K
D
Q
L
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22494
470
54194
D164
T
T
R
M
E
G
Q
D
L
Q
Y
Y
F
S
F
Sea Urchin
Strong. purpuratus
XP_783560
420
48731
Y140
L
T
T
Q
N
N
E
Y
I
Q
T
V
A
M
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX65
441
50266
Q161
L
V
E
W
L
C
A
Q
L
K
Q
P
S
H
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
N.A.
98.5
N.A.
98.5
89
N.A.
96
78
91.5
85
N.A.
52.5
N.A.
50.9
54.6
Protein Similarity:
100
98.5
N.A.
98.7
N.A.
99.3
90.2
N.A.
98.1
84.2
94.1
90
N.A.
71.8
N.A.
66.4
68.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
93.3
13.3
86.6
13.3
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
33.3
86.6
33.3
N.A.
33.3
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
24
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% D
% Glu:
8
0
8
8
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
16
0
8
0
0
0
8
8
0
8
% F
% Gly:
0
0
0
0
8
8
0
0
0
0
0
0
47
8
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
47
0
0
0
0
0
0
24
0
0
0
0
0
8
% I
% Lys:
0
0
47
0
0
0
0
0
0
77
0
0
0
0
0
% K
% Leu:
16
31
0
0
8
54
0
8
24
0
47
0
24
0
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
24
0
8
8
16
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
0
0
0
8
47
0
16
8
47
16
8
24
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
47
0
0
0
% R
% Ser:
0
0
0
8
0
8
47
47
0
0
0
0
8
62
24
% S
% Thr:
8
16
8
39
0
0
0
0
0
0
24
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
47
0
0
8
0
0
0
16
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
16
24
0
0
8
0
8
16
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _