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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V1H All Species: 22.12
Human Site: S192 Identified Species: 40.56
UniProt: Q9UI12 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI12 NP_057025.2 483 55883 S192 E T G T V S S S D S S Q Y V Q
Chimpanzee Pan troglodytes XP_001150191 483 55912 S192 E T G T V S S S D S S Q Y V Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544082 483 55817 S192 E T G T V S S S D S S Q Y V Q
Cat Felis silvestris
Mouse Mus musculus Q8BVE3 483 55836 S192 E T G T I S S S D S S Q Y V Q
Rat Rattus norvegicus NP_001013951 441 50841 G179 L S S Q K L R G S G V A V E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515210 483 55883 S192 E T G T V S P S D S S Q Y V Q
Chicken Gallus gallus XP_423862 445 52062 E182 R G T G G S V E A G A V S T S
Frog Xenopus laevis NP_001089309 479 55249 S188 E T G T V S P S D S S Q Y V Q
Zebra Danio Brachydanio rerio NP_775377 463 53422 G181 Q Y V Q C V A G C L Q L M L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J1 468 53715 R182 E Y I Q S V A R C L Q M M L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22494 470 54194 N182 Q L K N S T T N D Y M N T T A
Sea Urchin Strong. purpuratus XP_783560 420 48731 R158 M L K Y N E Y R V G F M A N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LX65 441 50266 L179 V P I A I S C L S S L L K E P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 N.A. 98.5 N.A. 98.5 89 N.A. 96 78 91.5 85 N.A. 52.5 N.A. 50.9 54.6
Protein Similarity: 100 98.5 N.A. 98.7 N.A. 99.3 90.2 N.A. 98.1 84.2 94.1 90 N.A. 71.8 N.A. 66.4 68.5
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 0 N.A. 93.3 6.6 93.3 0 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 93.3 13.3 93.3 26.6 N.A. 26.6 N.A. 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 16 0 8 0 8 8 8 0 8 % A
% Cys: 0 0 0 0 8 0 8 0 16 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 54 0 0 0 0 0 8 % D
% Glu: 54 0 0 0 0 8 0 8 0 0 0 0 0 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 47 8 8 0 0 16 0 24 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 0 16 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 16 0 8 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 16 0 0 0 8 0 8 0 16 8 16 0 16 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 8 16 16 0 0 % M
% Asn: 0 0 0 8 8 0 0 8 0 0 0 8 0 8 0 % N
% Pro: 0 8 0 0 0 0 16 0 0 0 0 0 0 0 8 % P
% Gln: 16 0 0 24 0 0 0 0 0 0 16 47 0 0 47 % Q
% Arg: 8 0 0 0 0 0 8 16 0 0 0 0 0 0 16 % R
% Ser: 0 8 8 0 16 62 31 47 16 54 47 0 8 0 8 % S
% Thr: 0 47 8 47 0 8 8 0 0 0 0 0 8 16 8 % T
% Val: 8 0 8 0 39 16 8 0 8 0 8 8 8 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 8 0 0 8 0 0 8 0 0 47 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _