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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMGDH
All Species:
24.55
Human Site:
S238
Identified Species:
90
UniProt:
Q9UI17
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI17
NP_037523.2
866
96811
S238
D
V
E
T
P
Q
G
S
M
R
A
N
R
I
V
Chimpanzee
Pan troglodytes
XP_526883
866
96847
S238
D
V
E
T
P
Q
G
S
M
R
A
N
R
I
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546052
875
97653
S247
D
V
E
T
P
Q
G
S
V
R
A
N
R
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT9
869
97236
S231
D
V
E
T
P
Q
G
S
V
R
A
N
R
I
V
Rat
Rattus norvegicus
Q63342
857
96029
S231
D
V
E
T
P
Q
G
S
V
R
A
N
R
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087085
870
97269
T245
N
V
V
T
Q
H
G
T
I
H
A
K
R
I
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792268
876
97060
T242
D
V
V
T
N
E
G
T
I
H
A
Q
R
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
90.1
N.A.
89.3
90.4
N.A.
N.A.
N.A.
76.5
N.A.
N.A.
N.A.
N.A.
N.A.
52.8
Protein Similarity:
100
99.6
N.A.
94.2
N.A.
93.4
94.2
N.A.
N.A.
N.A.
86.4
N.A.
N.A.
N.A.
N.A.
N.A.
70.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
86
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
72
0
0
15
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
29
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
29
0
0
0
0
86
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
15
0
0
0
0
0
0
72
0
0
0
% N
% Pro:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
72
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
72
0
0
100
0
0
% R
% Ser:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
100
0
0
0
29
0
0
0
0
0
0
0
% T
% Val:
0
100
29
0
0
0
0
0
43
0
0
0
0
15
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _