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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DMGDH All Species: 22.73
Human Site: Y312 Identified Species: 83.33
UniProt: Q9UI17 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI17 NP_037523.2 866 96811 Y312 D G L L F G P Y E S Q E K M K
Chimpanzee Pan troglodytes XP_526883 866 96847 Y312 D G L L F G P Y E S Q E K M K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546052 875 97653 Y321 D G L L F G P Y E S Q E K M K
Cat Felis silvestris
Mouse Mus musculus Q9DBT9 869 97236 Y305 D G L L F G P Y E S Q E K M K
Rat Rattus norvegicus Q63342 857 96029 Y305 D G L L F G P Y E S Q E K M K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087085 870 97269 Y319 D G L L F G P Y E N Q E K M K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792268 876 97060 H323 L R Q G F E P H T L W F T V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 90.1 N.A. 89.3 90.4 N.A. N.A. N.A. 76.5 N.A. N.A. N.A. N.A. N.A. 52.8
Protein Similarity: 100 99.6 N.A. 94.2 N.A. 93.4 94.2 N.A. N.A. N.A. 86.4 N.A. N.A. N.A. N.A. N.A. 70.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 93.3 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 15 0 0 86 0 0 86 0 0 0 % E
% Phe: 0 0 0 0 100 0 0 0 0 0 0 15 0 0 0 % F
% Gly: 0 86 0 15 0 86 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 86 0 86 % K
% Leu: 15 0 86 86 0 0 0 0 0 15 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 86 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 15 0 0 0 0 0 0 0 86 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 15 % R
% Ser: 0 0 0 0 0 0 0 0 0 72 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 15 0 0 0 15 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 86 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _