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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IPO11 All Species: 30.61
Human Site: S656 Identified Species: 56.11
UniProt: Q9UI26 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI26 NP_001128251.1 975 112535 S656 I Q L S T D V S Q P P H V Y L
Chimpanzee Pan troglodytes XP_001136141 975 112571 S656 I Q L S T D V S Q P P H V Y L
Rhesus Macaque Macaca mulatta XP_001082664 975 112574 S656 I Q L S T D V S Q P P H V Y L
Dog Lupus familis XP_535251 975 112368 S656 I Q L S T D V S Q P P H V Y L
Cat Felis silvestris
Mouse Mus musculus Q8K2V6 975 112397 S656 I Q L S T D V S Q P P H V Y L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505923 876 100629 T596 M L R C A I L T T L I H L V Q
Chicken Gallus gallus
Frog Xenopus laevis NP_001084723 975 111526 S656 I Q L S T D V S Q P P H V Y L
Zebra Danio Brachydanio rerio NP_001153133 961 110173 L656 L L E D G L E L W L V T L E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788357 1075 122024 Q706 I E L S T D L Q Q P S H V Y L
Honey Bee Apis mellifera XP_396286 968 110711 N653 I A L S C D V N Q D C H V Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793829 969 110950 S656 I K F S T D V S Q P P H V Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187508 1010 113955 N689 L Q K G I D I N S P D S L N L
Baker's Yeast Sacchar. cerevisiae Q02932 1032 119604 S678 V A L A C D P S S M Q Y Q L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.6 98.6 N.A. 96.8 N.A. N.A. 82.4 N.A. 81.6 82.6 N.A. 34.1 46.3 N.A. 50.6
Protein Similarity: 100 99.9 99.7 99.9 N.A. 98.3 N.A. N.A. 86.6 N.A. 91.9 90.8 N.A. 56.8 67.4 N.A. 69.5
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 N.A. 100 0 N.A. 73.3 66.6 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 33.3 N.A. 100 13.3 N.A. 86.6 73.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 29.1 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.2 47.7 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 8 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 8 16 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 8 0 85 0 0 0 8 8 0 0 0 0 % D
% Glu: 0 8 8 0 0 0 8 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 77 0 0 0 % H
% Ile: 70 0 0 0 8 8 8 0 0 0 8 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 16 70 0 0 8 16 8 0 16 0 0 24 8 85 % L
% Met: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 0 0 0 0 8 8 % N
% Pro: 0 0 0 0 0 0 8 0 0 70 54 0 0 0 0 % P
% Gln: 0 54 0 0 0 0 0 8 70 0 8 0 8 0 8 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 70 0 0 0 62 16 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 62 0 0 8 8 0 0 8 0 0 0 % T
% Val: 8 0 0 0 0 0 62 0 0 0 8 0 70 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 70 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _