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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPO11
All Species:
22.73
Human Site:
S718
Identified Species:
41.67
UniProt:
Q9UI26
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI26
NP_001128251.1
975
112535
S718
N
G
Y
I
F
L
S
S
T
E
F
L
Q
T
Y
Chimpanzee
Pan troglodytes
XP_001136141
975
112571
S718
N
G
Y
I
F
L
S
S
T
E
F
L
Q
T
Y
Rhesus Macaque
Macaca mulatta
XP_001082664
975
112574
S718
N
G
Y
I
F
L
S
S
T
E
F
L
Q
T
Y
Dog
Lupus familis
XP_535251
975
112368
S718
N
G
Y
I
F
L
S
S
T
E
F
L
Q
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2V6
975
112397
S718
N
G
Y
I
F
L
S
S
T
E
F
L
Q
T
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505923
876
100629
R658
C
L
T
P
E
L
L
R
I
F
Q
N
M
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084723
975
111526
S718
N
A
Y
I
F
S
S
S
S
E
F
L
Q
I
Y
Zebra Danio
Brachydanio rerio
NP_001153133
961
110173
S718
Y
A
E
A
L
C
R
S
F
C
E
L
L
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788357
1075
122024
A768
H
A
Y
I
L
L
D
A
Q
A
Y
L
S
R
Y
Honey Bee
Apis mellifera
XP_396286
968
110711
P715
Q
A
Y
V
I
L
S
P
Q
E
F
L
S
Q
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793829
969
110950
K718
S
S
Y
V
I
L
G
K
E
Q
F
M
Q
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187508
1010
113955
G751
D
S
Y
I
I
L
D
G
G
E
F
L
N
M
H
Baker's Yeast
Sacchar. cerevisiae
Q02932
1032
119604
A740
L
E
I
I
K
S
Y
A
L
I
L
N
P
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.6
98.6
N.A.
96.8
N.A.
N.A.
82.4
N.A.
81.6
82.6
N.A.
34.1
46.3
N.A.
50.6
Protein Similarity:
100
99.9
99.7
99.9
N.A.
98.3
N.A.
N.A.
86.6
N.A.
91.9
90.8
N.A.
56.8
67.4
N.A.
69.5
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
N.A.
73.3
13.3
N.A.
33.3
40
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
N.A.
80
20
N.A.
53.3
46.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
8
0
0
0
16
0
8
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
16
% D
% Glu:
0
8
8
0
8
0
0
0
8
62
8
0
0
0
0
% E
% Phe:
0
0
0
0
47
0
0
0
8
8
70
0
0
0
0
% F
% Gly:
0
39
0
0
0
0
8
8
8
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
8
70
24
0
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
16
77
8
0
8
0
8
77
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% M
% Asn:
47
0
0
0
0
0
0
0
0
0
0
16
8
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
16
8
8
0
54
8
0
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
8
% R
% Ser:
8
16
0
0
0
16
54
54
8
0
0
0
16
24
0
% S
% Thr:
0
0
8
0
0
0
0
0
39
0
0
0
0
39
0
% T
% Val:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
77
0
0
0
8
0
0
0
8
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _