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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IPO11 All Species: 33.94
Human Site: S848 Identified Species: 62.22
UniProt: Q9UI26 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI26 NP_001128251.1 975 112535 S848 Q P E R R K L S A L A L L S L
Chimpanzee Pan troglodytes XP_001136141 975 112571 S848 Q P E R R K L S A L A L L S L
Rhesus Macaque Macaca mulatta XP_001082664 975 112574 S848 Q P E R R K L S A L A L L S L
Dog Lupus familis XP_535251 975 112368 S848 Q P E R R K L S A L A L L S L
Cat Felis silvestris
Mouse Mus musculus Q8K2V6 975 112397 S848 Q P E R K K L S A L A L L S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505923 876 100629 Y755 G I I D G E R Y P V V M S T Y
Chicken Gallus gallus
Frog Xenopus laevis NP_001084723 975 111526 S848 Q P E R R K L S A L A L L S L
Zebra Danio Brachydanio rerio NP_001153133 961 110173 S834 Q P E R R K L S A L A L L S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788357 1075 122024 F894 H A E K R K L F C L A F A S I
Honey Bee Apis mellifera XP_396286 968 110711 L837 Q L E R R K L L A L A L C S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793829 969 110950 T848 A A E R R K L T G L A F A S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187508 1010 113955 S884 L D K V D H A S P M Q Q K T F
Baker's Yeast Sacchar. cerevisiae Q02932 1032 119604 T884 S V V N K L L T G W I V C F R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.6 98.6 N.A. 96.8 N.A. N.A. 82.4 N.A. 81.6 82.6 N.A. 34.1 46.3 N.A. 50.6
Protein Similarity: 100 99.9 99.7 99.9 N.A. 98.3 N.A. N.A. 86.6 N.A. 91.9 90.8 N.A. 56.8 67.4 N.A. 69.5
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 0 N.A. 100 100 N.A. 46.6 80 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 26.6 N.A. 100 100 N.A. 60 80 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 29.1 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. 52.2 47.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 0 0 0 8 0 62 0 77 0 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 16 0 0 % C
% Asp: 0 8 0 8 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 77 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 16 0 8 8 % F
% Gly: 8 0 0 0 8 0 0 0 16 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 8 0 0 0 8 % I
% Lys: 0 0 8 8 16 77 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 8 0 0 0 8 85 8 0 77 0 62 54 0 70 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 54 0 0 0 0 0 0 16 0 0 0 0 0 0 % P
% Gln: 62 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 0 0 70 70 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 8 0 0 0 0 0 0 62 0 0 0 0 8 77 0 % S
% Thr: 0 0 0 0 0 0 0 16 0 0 0 0 0 16 0 % T
% Val: 0 8 8 8 0 0 0 0 0 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _