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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLS2
All Species:
31.82
Human Site:
S519
Identified Species:
70
UniProt:
Q9UI32
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI32
NP_037399.2
602
66323
S519
M
E
Q
K
D
Y
D
S
R
T
A
L
H
V
A
Chimpanzee
Pan troglodytes
XP_509148
602
66304
S519
M
E
Q
K
D
Y
D
S
R
T
A
L
H
V
A
Rhesus Macaque
Macaca mulatta
XP_001115245
602
66544
S519
M
E
Q
K
D
Y
D
S
R
T
A
L
H
V
A
Dog
Lupus familis
XP_545570
679
74042
S596
M
E
Q
R
D
Y
D
S
R
T
A
L
H
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q571F8
602
66347
S519
M
E
Q
K
D
Y
D
S
R
T
A
L
H
V
A
Rat
Rattus norvegicus
P28492
602
66229
S519
M
E
Q
K
D
Y
D
S
R
T
A
L
H
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026419
668
73493
S564
M
E
Q
R
D
Y
D
S
R
T
A
L
H
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038509
591
65834
S509
M
E
Q
R
D
Y
D
S
R
T
A
L
H
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725213
716
79809
G579
I
T
L
A
D
Y
D
G
R
T
A
L
H
L
A
Honey Bee
Apis mellifera
XP_392523
614
69191
G522
M
T
L
S
D
Y
D
G
R
T
A
L
H
L
A
Nematode Worm
Caenorhab. elegans
Q19013
605
68317
D514
L
N
T
S
D
H
D
D
R
T
V
L
H
I
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.5
62.5
N.A.
94.3
94.3
N.A.
N.A.
61.9
N.A.
66.7
N.A.
41.7
48.3
44.7
N.A.
Protein Similarity:
100
100
98.5
73.3
N.A.
96.5
96.6
N.A.
N.A.
74
N.A.
80.4
N.A.
57.8
66.2
63.9
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
60
66.6
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
73.3
73.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
91
0
0
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
100
0
100
10
0
0
0
0
0
0
0
% D
% Glu:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
100
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
19
0
0
0
0
0
0
0
0
100
0
19
0
% L
% Met:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
28
0
0
0
0
100
0
0
0
0
0
0
% R
% Ser:
0
0
0
19
0
0
0
73
0
0
0
0
0
0
0
% S
% Thr:
0
19
10
0
0
0
0
0
0
100
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _