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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DACH1
All Species:
7.27
Human Site:
S518
Identified Species:
20
UniProt:
Q9UI36
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI36
NP_004383.2
758
78562
S518
H
R
S
S
S
V
S
S
S
P
A
R
T
E
S
Chimpanzee
Pan troglodytes
XP_522679
709
73348
S498
N
Q
M
L
M
G
L
S
P
N
V
L
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001082626
706
72982
S495
N
Q
M
L
M
G
L
S
P
N
V
L
P
G
P
Dog
Lupus familis
XP_542608
514
56264
G313
V
L
P
G
P
K
E
G
D
L
A
G
H
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYB2
751
77953
S511
H
R
S
S
S
V
S
S
S
P
A
R
T
E
S
Rat
Rattus norvegicus
XP_001055336
614
66170
N413
R
M
V
M
M
P
N
N
R
E
E
I
I
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417018
660
69358
G459
V
L
P
G
P
K
E
G
D
L
A
G
H
D
M
Frog
Xenopus laevis
NP_001088747
610
66220
S409
R
V
A
L
L
T
N
S
R
E
G
E
I
T
G
Zebra Danio
Brachydanio rerio
NP_001074142
611
65712
K410
P
S
I
L
P
G
P
K
E
G
D
L
A
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
92.2
60.1
N.A.
92.8
51.1
N.A.
N.A.
81.1
49
68.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.8
92.8
62.9
N.A.
94.3
62.5
N.A.
N.A.
84.1
60.5
74
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
100
0
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
13.3
N.A.
100
13.3
N.A.
N.A.
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
0
45
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
23
0
12
0
0
23
23
% D
% Glu:
0
0
0
0
0
0
23
0
12
23
12
12
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
23
0
34
0
23
0
12
12
23
0
23
12
% G
% His:
23
0
0
0
0
0
0
0
0
0
0
0
23
12
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
12
23
12
0
% I
% Lys:
0
0
0
0
0
23
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
23
0
45
12
0
23
0
0
23
0
34
0
0
0
% L
% Met:
0
12
23
12
34
0
0
0
0
0
0
0
0
0
23
% M
% Asn:
23
0
0
0
0
0
23
12
0
23
0
0
0
0
0
% N
% Pro:
12
0
23
0
34
12
12
0
23
23
0
0
23
0
23
% P
% Gln:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
23
23
0
0
0
0
0
0
23
0
0
23
0
0
0
% R
% Ser:
0
12
23
23
23
0
23
56
23
0
0
0
0
0
23
% S
% Thr:
0
0
0
0
0
12
0
0
0
0
0
0
23
12
0
% T
% Val:
23
12
12
0
0
23
0
0
0
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _