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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DACH1 All Species: 14.85
Human Site: S725 Identified Species: 40.83
UniProt: Q9UI36 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI36 NP_004383.2 758 78562 S725 S L R V L N D S L T P E I E A
Chimpanzee Pan troglodytes XP_522679 709 73348 S676 S L R V L N D S L T P E I E A
Rhesus Macaque Macaca mulatta XP_001082626 706 72982 S673 S L R V L N E S L T P E I E A
Dog Lupus familis XP_542608 514 56264 L482 L R V L N D S L T P E I E A D
Cat Felis silvestris
Mouse Mus musculus Q9QYB2 751 77953 S718 S L R V L N D S L T P E I E A
Rat Rattus norvegicus XP_001055336 614 66170 L582 G D S G L R M L K D S G I P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417018 660 69358 L628 L R V L N D S L T P E I E A D
Frog Xenopus laevis NP_001088747 610 66220 A578 G L R M L N D A C I P E M E T
Zebra Danio Brachydanio rerio NP_001074142 611 65712 T579 R S L N D S L T Q E I E T D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 92.2 60.1 N.A. 92.8 51.1 N.A. N.A. 81.1 49 68.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.8 92.8 62.9 N.A. 94.3 62.5 N.A. N.A. 84.1 60.5 74 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 0 N.A. 100 13.3 N.A. N.A. 0 53.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 13.3 N.A. N.A. 13.3 73.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 0 0 0 23 45 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 12 23 45 0 0 12 0 0 0 12 34 % D
% Glu: 0 0 0 0 0 0 12 0 0 12 23 67 23 56 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 23 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 12 23 56 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % K
% Leu: 23 56 12 23 67 0 12 34 45 0 0 0 0 0 0 % L
% Met: 0 0 0 12 0 0 12 0 0 0 0 0 12 0 0 % M
% Asn: 0 0 0 12 23 56 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 23 56 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 12 23 56 0 0 12 0 0 0 0 0 0 0 0 12 % R
% Ser: 45 12 12 0 0 12 23 45 0 0 12 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 12 23 45 0 0 12 0 12 % T
% Val: 0 0 23 45 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _