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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAD2L2 All Species: 22.73
Human Site: S111 Identified Species: 45.45
UniProt: Q9UI95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI95 NP_001120797.1 211 24334 S111 Q P P L L S I S S D S L L S H
Chimpanzee Pan troglodytes XP_514391 289 31985 S189 P C P L A G I S S D S L L S H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544568 196 22705 S96 Q P P L L S I S S D S L L S H
Cat Felis silvestris
Mouse Mus musculus Q9D752 211 24384 N111 Q P P L L S I N S D S L L S H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507810 211 24383 S111 Q P P L L S I S S D S L L S H
Chicken Gallus gallus NP_001020749 211 24328 S111 Q P P L L S I S S E S L L S H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017595 211 24206 S111 Q P P L L A I S S E T L L S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798371 146 16656 C66 F L L R L N T C D A V L H S L
Poplar Tree Populus trichocarpa XP_002332204 207 23752 G104 L A M D Q S Y G S K V E E G D
Maize Zea mays Q9XFH3 208 23486 I116 E V V E K G A I K E K S D K E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU93 209 23713 S117 E V V D K G V S R E K S D K E
Baker's Yeast Sacchar. cerevisiae P40958 196 22266 Q99 E R W S F N V Q H I S G N S N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73 N.A. 85.3 N.A. 98.5 N.A. N.A. 97.6 96.6 N.A. 84.8 N.A. N.A. N.A. N.A. 29.8
Protein Similarity: 100 73 N.A. 86.7 N.A. 99 N.A. N.A. 99 99 N.A. 94.7 N.A. N.A. N.A. N.A. 47.3
P-Site Identity: 100 73.3 N.A. 100 N.A. 93.3 N.A. N.A. 100 93.3 N.A. 80 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 73.3 N.A. 100 N.A. 100 N.A. N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 27.9 22.2 N.A. 21.8 27 N.A.
Protein Similarity: 53.5 46.4 N.A. 42.1 46.4 N.A.
P-Site Identity: 13.3 0 N.A. 6.6 13.3 N.A.
P-Site Similarity: 13.3 13.3 N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 9 0 0 9 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 0 0 0 0 9 42 0 0 17 0 9 % D
% Glu: 25 0 0 9 0 0 0 0 0 34 0 9 9 0 17 % E
% Phe: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 25 0 9 0 0 0 9 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 59 % H
% Ile: 0 0 0 0 0 0 59 9 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 17 0 0 0 9 9 17 0 0 17 0 % K
% Leu: 9 9 9 59 59 0 0 0 0 0 0 67 59 0 9 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 17 0 9 0 0 0 0 9 0 9 % N
% Pro: 9 50 59 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 50 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 50 0 59 67 0 59 17 0 75 0 % S
% Thr: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % T
% Val: 0 17 17 0 0 0 17 0 0 0 17 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _