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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD2L2
All Species:
30
Human Site:
S117
Identified Species:
60
UniProt:
Q9UI95
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI95
NP_001120797.1
211
24334
S117
I
S
S
D
S
L
L
S
H
V
E
Q
L
L
R
Chimpanzee
Pan troglodytes
XP_514391
289
31985
S195
I
S
S
D
S
L
L
S
H
V
E
Q
L
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544568
196
22705
S102
I
S
S
D
S
L
L
S
H
V
E
Q
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D752
211
24384
S117
I
N
S
D
S
L
L
S
H
V
E
Q
L
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507810
211
24383
S117
I
S
S
D
S
L
L
S
H
V
E
Q
L
L
R
Chicken
Gallus gallus
NP_001020749
211
24328
S117
I
S
S
E
S
L
L
S
H
V
E
Q
L
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017595
211
24206
S117
I
S
S
E
T
L
L
S
H
V
E
Q
L
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798371
146
16656
S72
T
C
D
A
V
L
H
S
L
P
Q
D
C
T
F
Poplar Tree
Populus trichocarpa
XP_002332204
207
23752
G110
Y
G
S
K
V
E
E
G
D
L
E
F
S
L
R
Maize
Zea mays
Q9XFH3
208
23486
K122
A
I
K
E
K
S
D
K
E
I
M
R
E
I
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU93
209
23713
K123
V
S
R
E
K
S
D
K
E
I
M
R
E
I
Q
Baker's Yeast
Sacchar. cerevisiae
P40958
196
22266
S105
V
Q
H
I
S
G
N
S
N
G
Q
D
D
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73
N.A.
85.3
N.A.
98.5
N.A.
N.A.
97.6
96.6
N.A.
84.8
N.A.
N.A.
N.A.
N.A.
29.8
Protein Similarity:
100
73
N.A.
86.7
N.A.
99
N.A.
N.A.
99
99
N.A.
94.7
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
N.A.
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
27.9
22.2
N.A.
21.8
27
N.A.
Protein Similarity:
53.5
46.4
N.A.
42.1
46.4
N.A.
P-Site Identity:
26.6
0
N.A.
6.6
13.3
N.A.
P-Site Similarity:
33.3
33.3
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
42
0
0
17
0
9
0
0
17
9
0
0
% D
% Glu:
0
0
0
34
0
9
9
0
17
0
67
0
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
0
9
0
0
0
9
0
9
0
9
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
9
0
59
0
0
0
0
0
0
% H
% Ile:
59
9
0
9
0
0
0
0
0
17
0
0
0
17
0
% I
% Lys:
0
0
9
9
17
0
0
17
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
67
59
0
9
9
0
0
59
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
17
59
0
0
17
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
17
0
0
67
% R
% Ser:
0
59
67
0
59
17
0
75
0
0
0
0
9
0
0
% S
% Thr:
9
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% T
% Val:
17
0
0
0
17
0
0
0
0
59
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _