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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAD2L2 All Species: 33.94
Human Site: T191 Identified Species: 67.88
UniProt: Q9UI95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI95 NP_001120797.1 211 24334 T191 P R L I P L K T M T S D I L K
Chimpanzee Pan troglodytes XP_514391 289 31985 T269 P R L I P L K T M T S D I L K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544568 196 22705 T176 P R L I P L K T M T S D I L K
Cat Felis silvestris
Mouse Mus musculus Q9D752 211 24384 T191 P R L I P L K T M T S D I L K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507810 211 24383 T191 P R L I P L K T M T S D I L K
Chicken Gallus gallus NP_001020749 211 24328 T191 P R L I P L K T M T S D I L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017595 211 24206 T191 A K L I P L K T M T S D I L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798371 146 16656 S127 V P L K A V S S D L L K M Q L
Poplar Tree Populus trichocarpa XP_002332204 207 23752 S179 S L I T P I K S M S S E P L S
Maize Zea mays Q9XFH3 208 23486 S185 P Q M V K L H S F D T K I H K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU93 209 23713 G186 P Q M V K L H G F D T K I H K
Baker's Yeast Sacchar. cerevisiae P40958 196 22266 W162 D A K V P L E W A D S N S K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73 N.A. 85.3 N.A. 98.5 N.A. N.A. 97.6 96.6 N.A. 84.8 N.A. N.A. N.A. N.A. 29.8
Protein Similarity: 100 73 N.A. 86.7 N.A. 99 N.A. N.A. 99 99 N.A. 94.7 N.A. N.A. N.A. N.A. 47.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 27.9 22.2 N.A. 21.8 27 N.A.
Protein Similarity: 53.5 46.4 N.A. 42.1 46.4 N.A.
P-Site Identity: 33.3 26.6 N.A. 26.6 20 N.A.
P-Site Similarity: 66.6 60 N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 9 25 0 59 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 17 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 9 59 0 9 0 0 0 0 0 0 75 0 0 % I
% Lys: 0 9 9 9 17 0 67 0 0 0 0 25 0 9 75 % K
% Leu: 0 9 67 0 0 84 0 0 0 9 9 0 0 67 9 % L
% Met: 0 0 17 0 0 0 0 0 67 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 67 9 0 0 75 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 17 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 9 25 0 9 75 0 9 0 9 % S
% Thr: 0 0 0 9 0 0 0 59 0 59 17 0 0 0 0 % T
% Val: 9 0 0 25 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _