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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD2L2
All Species:
22.73
Human Site:
T67
Identified Species:
45.45
UniProt:
Q9UI95
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI95
NP_001120797.1
211
24334
T67
L
N
Q
Y
I
Q
D
T
L
H
C
V
K
P
L
Chimpanzee
Pan troglodytes
XP_514391
289
31985
T132
L
N
Q
Y
I
Q
D
T
L
H
C
V
K
P
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544568
196
22705
L73
E
K
V
V
V
V
I
L
D
K
E
H
R
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D752
211
24384
T67
L
N
Q
Y
I
Q
D
T
L
H
C
V
K
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507810
211
24383
T67
L
N
Q
Y
I
Q
D
T
L
H
C
V
K
P
L
Chicken
Gallus gallus
NP_001020749
211
24328
T67
L
N
Q
Y
I
Q
D
T
L
H
C
V
K
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017595
211
24206
T67
L
N
Q
Y
I
Q
D
T
L
H
C
V
K
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798371
146
16656
D43
R
P
S
T
N
K
I
D
S
I
E
N
R
L
E
Poplar Tree
Populus trichocarpa
XP_002332204
207
23752
A62
L
R
D
Y
I
H
S
A
V
S
G
L
L
P
F
Maize
Zea mays
Q9XFH3
208
23486
L68
V
K
N
F
I
A
S
L
T
S
Q
L
S
E
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU93
209
23713
L69
V
K
S
F
M
S
N
L
T
S
Q
I
S
E
W
Baker's Yeast
Sacchar. cerevisiae
P40958
196
22266
I62
L
K
D
Y
I
R
K
I
L
L
Q
V
H
R
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73
N.A.
85.3
N.A.
98.5
N.A.
N.A.
97.6
96.6
N.A.
84.8
N.A.
N.A.
N.A.
N.A.
29.8
Protein Similarity:
100
73
N.A.
86.7
N.A.
99
N.A.
N.A.
99
99
N.A.
94.7
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
N.A.
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
27.9
22.2
N.A.
21.8
27
N.A.
Protein Similarity:
53.5
46.4
N.A.
42.1
46.4
N.A.
P-Site Identity:
26.6
6.6
N.A.
0
33.3
N.A.
P-Site Similarity:
40
26.6
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
50
9
9
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
17
0
0
17
9
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
50
0
9
9
0
0
% H
% Ile:
0
0
0
0
75
0
17
9
0
9
0
9
0
0
0
% I
% Lys:
0
34
0
0
0
9
9
0
0
9
0
0
50
0
0
% K
% Leu:
67
0
0
0
0
0
0
25
59
9
0
17
9
9
50
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
50
9
0
9
0
9
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
67
0
% P
% Gln:
0
0
50
0
0
50
0
0
0
0
25
0
0
0
0
% Q
% Arg:
9
9
0
0
0
9
0
0
0
0
0
0
17
9
0
% R
% Ser:
0
0
17
0
0
9
17
0
9
25
0
0
17
0
0
% S
% Thr:
0
0
0
9
0
0
0
50
17
0
0
0
0
0
0
% T
% Val:
17
0
9
9
9
9
0
0
9
0
0
59
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% W
% Tyr:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _