Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAD2L2 All Species: 30.61
Human Site: Y48 Identified Species: 61.21
UniProt: Q9UI95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI95 NP_001120797.1 211 24334 Y48 I F Q K R K K Y N V P V Q M S
Chimpanzee Pan troglodytes XP_514391 289 31985 Y113 I F Q K R K K Y N V P V Q M S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544568 196 22705 H54 Q Y I Q D T L H C V K P L L E
Cat Felis silvestris
Mouse Mus musculus Q9D752 211 24384 Y48 I F Q K R K K Y N V P V Q M S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507810 211 24383 Y48 I F Q K R K K Y N V P V Q M S
Chicken Gallus gallus NP_001020749 211 24328 Y48 I F Q K R K K Y N V P V Q M S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017595 211 24206 Y48 I F Q K R Q K Y N V P V Q M S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798371 146 16656 H24 V V I L N A K H I P V E R F V
Poplar Tree Populus trichocarpa XP_002332204 207 23752 M43 A F E R R R Y M N V V V Q R A
Maize Zea mays Q9XFH3 208 23486 Y49 S F S K V K K Y G L T M L L T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU93 209 23713 Y50 S F V K V K K Y G L P M L L I
Baker's Yeast Sacchar. cerevisiae P40958 196 22266 Y43 D F V T V K K Y D L T L L K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73 N.A. 85.3 N.A. 98.5 N.A. N.A. 97.6 96.6 N.A. 84.8 N.A. N.A. N.A. N.A. 29.8
Protein Similarity: 100 73 N.A. 86.7 N.A. 99 N.A. N.A. 99 99 N.A. 94.7 N.A. N.A. N.A. N.A. 47.3
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 N.A. N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 33.3 N.A. 100 N.A. N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 27.9 22.2 N.A. 21.8 27 N.A.
Protein Similarity: 53.5 46.4 N.A. 42.1 46.4 N.A.
P-Site Identity: 40 33.3 N.A. 40 26.6 N.A.
P-Site Similarity: 66.6 60 N.A. 60 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 9 % E
% Phe: 0 84 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % H
% Ile: 50 0 17 0 0 0 0 0 9 0 0 0 0 0 9 % I
% Lys: 0 0 0 67 0 67 84 0 0 0 9 0 0 9 0 % K
% Leu: 0 0 0 9 0 0 9 0 0 25 0 9 34 25 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 17 0 50 0 % M
% Asn: 0 0 0 0 9 0 0 0 59 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 59 9 0 0 0 % P
% Gln: 9 0 50 9 0 9 0 0 0 0 0 0 59 0 0 % Q
% Arg: 0 0 0 9 59 9 0 0 0 0 0 0 9 9 0 % R
% Ser: 17 0 9 0 0 0 0 0 0 0 0 0 0 0 50 % S
% Thr: 0 0 0 9 0 9 0 0 0 0 17 0 0 0 17 % T
% Val: 9 9 17 0 25 0 0 0 0 67 17 59 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 9 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _