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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCMT1 All Species: 20
Human Site: Y118 Identified Species: 29.33
UniProt: Q9UIC8 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIC8 NP_001027563.1 334 38379 Y118 E D L L P S K Y F E V D F P M
Chimpanzee Pan troglodytes XP_523323 329 37684 Y118 E D L L P S K Y F E V D F P M
Rhesus Macaque Macaca mulatta XP_001099127 334 38216 Y118 E D L L P S K Y F E V D F P M
Dog Lupus familis XP_850461 545 61499 Y243 E D L L P S K Y F E V D F P M
Cat Felis silvestris
Mouse Mus musculus NP_079580 332 38173 L129 P M I V T R K L L T I K S K P
Rat Rattus norvegicus Q6P4Z6 332 38312 L129 P M I V T R K L H T I K N K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506013 820 89358 Y604 E N L L P V K Y F E V D F P M
Chicken Gallus gallus NP_001006167 234 27107 K35 A R K I H N I K S K P P L S K
Frog Xenopus laevis NP_001089458 326 37039 L123 P A I V A R K L Y N I K S K P
Zebra Danio Brachydanio rerio NP_001004645 325 37495 I122 P M I V A R K I H N I K T K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609766 337 38418 T121 F I E L D F P T V T A R K C Y
Honey Bee Apis mellifera XP_392837 312 35712 H113 I T A R K C Y H I K K H K Q L
Nematode Worm Caenorhab. elegans P46554 333 37797 Y127 S G A K L V K Y V E V D F S S
Sea Urchin Strong. purpuratus XP_789594 316 36250 P117 C Q N V R I R P K L T Q G V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04081 328 37676 F119 M L P L L Q M F P H L A Y V D
Red Bread Mold Neurospora crassa Q7SAP7 431 46728 K209 K A V A E K H K G S E L W V H
Conservation
Percent
Protein Identity: 100 98.1 98.5 55.2 N.A. 88.6 88.3 N.A. 34.2 51.2 66.4 63.7 N.A. 45 43.4 37.7 46.7
Protein Similarity: 100 98.1 99 58.7 N.A. 93.1 92.8 N.A. 37.7 60.4 80.8 79.9 N.A. 61.4 61 58 63.7
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 86.6 0 6.6 6.6 N.A. 6.6 0 40 0
P-Site Similarity: 100 100 100 100 N.A. 26.6 26.6 N.A. 93.3 20 33.3 26.6 N.A. 6.6 20 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.6 43.3
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 13 7 13 0 0 0 0 0 7 7 0 0 0 % A
% Cys: 7 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 25 0 0 7 0 0 0 0 0 0 38 0 0 7 % D
% Glu: 32 0 7 0 7 0 0 0 0 38 7 0 0 0 0 % E
% Phe: 7 0 0 0 0 7 0 7 32 0 0 0 38 0 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 0 0 0 7 0 0 % G
% His: 0 0 0 0 7 0 7 7 13 7 0 7 0 0 7 % H
% Ile: 7 7 25 7 0 7 7 7 7 0 25 0 0 0 0 % I
% Lys: 7 0 7 7 7 7 63 13 7 13 7 25 13 25 7 % K
% Leu: 0 7 32 44 13 0 0 19 7 7 7 7 7 0 7 % L
% Met: 7 19 0 0 0 0 7 0 0 0 0 0 0 0 32 % M
% Asn: 0 7 7 0 0 7 0 0 0 13 0 0 7 0 0 % N
% Pro: 25 0 7 0 32 0 7 7 7 0 7 7 0 32 25 % P
% Gln: 0 7 0 0 0 7 0 0 0 0 0 7 0 7 7 % Q
% Arg: 0 7 0 7 7 25 7 0 0 0 0 7 0 0 0 % R
% Ser: 7 0 0 0 0 25 0 0 7 7 0 0 13 13 7 % S
% Thr: 0 7 0 0 13 0 0 7 0 19 7 0 7 0 0 % T
% Val: 0 0 7 32 0 13 0 0 13 0 38 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 7 38 7 0 0 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _