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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FFR All Species: 22.73
Human Site: S486 Identified Species: 45.45
UniProt: Q9UID3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UID3 NP_037397.2 782 86042 S486 Y F R G E F C S Q G V R E G L
Chimpanzee Pan troglodytes XP_001168116 782 86012 S486 Y F R G E F C S Q G V R E G L
Rhesus Macaque Macaca mulatta XP_001114496 701 76841 G408 R V A R E R L G H H L Q G L R
Dog Lupus familis XP_533237 781 85755 S485 Y F R G E F C S Q G V R E G L
Cat Felis silvestris
Mouse Mus musculus Q3UVL4 782 86169 S486 Y F R G E F C S Q G V R E G L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ25 787 86041 V489 Y F K G E F C V E A V R E G L
Frog Xenopus laevis Q505L3 757 84769 S461 Y F K G E F C S Q G V R E G L
Zebra Danio Brachydanio rerio Q155U0 827 92298 S531 Y F K G E F C S Q G V R E G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MSY4 740 83919 L436 K A E H K G A L C V E G I R E
Honey Bee Apis mellifera XP_625224 735 84372 E439 L Q N F C V D E V R E G L V V
Nematode Worm Caenorhab. elegans O01839 700 78755 F414 P D E F R Q S F S F N A H E R
Sea Urchin Strong. purpuratus XP_787772 1151 131774 P507 L F F A T K Y P T K T V R E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 83.6 96.4 N.A. 95.7 N.A. N.A. N.A. 65.6 69.3 67.2 N.A. 41.8 46 28.1 38.1
Protein Similarity: 100 100 85.1 97.9 N.A. 97.6 N.A. N.A. N.A. 75.5 80.5 78.4 N.A. 58.9 61.8 47.7 49.3
P-Site Identity: 100 100 6.6 100 N.A. 100 N.A. N.A. N.A. 73.3 93.3 93.3 N.A. 0 0 0 6.6
P-Site Similarity: 100 100 20 100 N.A. 100 N.A. N.A. N.A. 86.6 100 100 N.A. 6.6 6.6 0 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 0 0 9 0 0 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 59 0 9 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 17 0 67 0 0 9 9 0 17 0 59 17 9 % E
% Phe: 0 67 9 17 0 59 0 9 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 59 0 9 0 9 0 50 0 17 9 59 9 % G
% His: 0 0 0 9 0 0 0 0 9 9 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 9 0 25 0 9 9 0 0 0 9 0 0 0 0 0 % K
% Leu: 17 0 0 0 0 0 9 9 0 0 9 0 9 9 59 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 9 0 0 50 0 0 9 0 0 0 % Q
% Arg: 9 0 34 9 9 9 0 0 0 9 0 59 9 9 17 % R
% Ser: 0 0 0 0 0 0 9 50 9 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 9 0 9 0 0 0 0 % T
% Val: 0 9 0 0 0 9 0 9 9 9 59 9 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 59 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _