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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUTYH
All Species:
20.3
Human Site:
T349
Identified Species:
40.61
UniProt:
Q9UIF7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UIF7
NP_001041636.1
546
60069
T349
P
S
E
P
W
D
Q
T
L
G
V
V
N
F
P
Chimpanzee
Pan troglodytes
XP_001155767
546
60211
T349
P
S
E
P
W
D
Q
T
L
G
V
V
N
F
P
Rhesus Macaque
Macaca mulatta
XP_001101469
533
58769
T335
A
S
E
P
W
D
Q
T
L
G
V
V
N
F
P
Dog
Lupus familis
XP_539632
573
63255
T375
P
T
E
P
W
D
Q
T
L
G
V
T
N
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99P21
515
57711
S320
P
S
S
P
W
D
P
S
M
G
V
A
N
F
P
Rat
Rattus norvegicus
Q8R5G2
516
57901
N320
S
T
N
P
W
D
P
N
M
G
V
V
N
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519000
605
64943
E351
P
T
E
P
W
N
R
E
L
G
V
T
N
L
P
Chicken
Gallus gallus
XP_422433
511
56150
S316
A
A
E
P
W
D
S
S
L
G
V
T
N
F
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686698
526
59141
Q321
L
S
E
D
W
D
P
Q
L
G
V
Q
N
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791369
425
47583
D244
L
C
M
D
G
P
V
D
A
N
L
G
V
M
N
Poplar Tree
Populus trichocarpa
XP_002321221
480
54779
A299
K
Q
R
H
E
F
S
A
V
C
A
V
E
I
T
Maize
Zea mays
NP_001150481
469
52213
P288
R
V
V
P
K
A
K
P
R
S
D
F
A
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.8
76.7
N.A.
73.4
73
N.A.
54.7
55.3
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
37.1
Protein Similarity:
100
99.6
94.6
83.4
N.A.
81.1
80.7
N.A.
64.9
67.2
N.A.
60.2
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
93.3
86.6
N.A.
66.6
60
N.A.
60
66.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
73.3
N.A.
80
80
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
33.7
32.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.6
48.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
9
0
9
9
0
9
9
9
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
67
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
0
59
0
9
0
0
9
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
9
0
59
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
75
0
9
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
0
0
0
0
0
0
59
0
9
0
0
9
0
% L
% Met:
0
0
9
0
0
0
0
0
17
0
0
0
0
9
0
% M
% Asn:
0
0
9
0
0
9
0
9
0
9
0
0
75
0
9
% N
% Pro:
42
0
0
75
0
9
25
9
0
0
0
0
0
0
75
% P
% Gln:
0
9
0
0
0
0
34
9
0
0
0
9
0
0
0
% Q
% Arg:
9
0
9
0
0
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
9
42
9
0
0
0
17
17
0
9
0
0
0
0
0
% S
% Thr:
0
25
0
0
0
0
0
34
0
0
0
25
0
0
9
% T
% Val:
0
9
9
0
0
0
9
0
9
0
75
42
9
0
9
% V
% Trp:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _