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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AK3 All Species: 21.52
Human Site: T110 Identified Species: 43.03
UniProt: Q9UIJ7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIJ7 NP_057366.2 227 25565 T110 D R A Y Q I D T V I N L N V P
Chimpanzee Pan troglodytes XP_001138039 227 25511 T110 H R A Y Q I D T V I N L N V P
Rhesus Macaque Macaca mulatta XP_001084982 227 25465 T110 D R A Y Q I D T V I N L N V P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WTP7 227 25408 T110 D K V Y Q I D T V I N L N V P
Rat Rattus norvegicus P29411 227 25420 T110 D R V Y Q I D T V I N L N V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505346 223 25113 K105 S Q A E A L N K V Y R I D T V
Chicken Gallus gallus XP_424173 185 21124 D70 C Q I D T V I D L D V P F E T
Frog Xenopus laevis NP_001084561 221 24864 K103 S Q A M A L D K A F H I N S V
Zebra Danio Brachydanio rerio NP_998295 214 23816 V99 C V Y D V D S V I N L D V P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788479 220 25045 Q103 E A L S K N Q Q I D T V M N L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141169 227 25476 T110 D R V Y Q I D T V I N L N V P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FK35 248 27317 E132 T Q A E K L D E M L N R R G A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.6 N.A. N.A. 92.5 90.7 N.A. 66.9 59.9 72.2 62.5 N.A. N.A. N.A. N.A. 61.2
Protein Similarity: 100 99.1 99.1 N.A. N.A. 96 93.8 N.A. 75.3 72.6 81.5 76.6 N.A. N.A. N.A. N.A. 73.5
P-Site Identity: 100 93.3 100 N.A. N.A. 86.6 93.3 N.A. 13.3 0 20 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 100 N.A. N.A. 93.3 93.3 N.A. 46.6 20 46.6 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 92.5 N.A. 42.3 N.A. N.A.
Protein Similarity: N.A. 95.1 N.A. 58.4 N.A. N.A.
P-Site Identity: N.A. 93.3 N.A. 20 N.A. N.A.
P-Site Similarity: N.A. 93.3 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 50 0 17 0 0 0 9 0 0 0 0 0 9 % A
% Cys: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 42 0 0 17 0 9 67 9 0 17 0 9 9 0 0 % D
% Glu: 9 0 0 17 0 0 0 9 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 9 0 0 50 9 0 17 50 0 17 0 0 0 % I
% Lys: 0 9 0 0 17 0 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 25 0 0 9 9 9 50 0 0 9 % L
% Met: 0 0 0 9 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 9 9 0 0 9 59 0 59 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 50 % P
% Gln: 0 34 0 0 50 0 9 9 0 0 0 0 0 0 0 % Q
% Arg: 0 42 0 0 0 0 0 0 0 0 9 9 9 0 0 % R
% Ser: 17 0 0 9 0 0 9 0 0 0 0 0 0 9 0 % S
% Thr: 9 0 0 0 9 0 0 50 0 0 9 0 0 9 9 % T
% Val: 0 9 25 0 9 9 0 9 59 0 9 9 9 50 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 50 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _