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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAPK2
All Species:
25.15
Human Site:
S349
Identified Species:
50.3
UniProt:
Q9UIK4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UIK4
NP_055141.2
370
42898
S349
E
D
L
R
N
C
E
S
D
T
E
E
D
I
A
Chimpanzee
Pan troglodytes
XP_001157721
505
56356
S484
E
D
L
R
N
C
E
S
D
T
E
E
D
I
A
Rhesus Macaque
Macaca mulatta
XP_001106327
370
42824
S349
E
D
L
R
N
C
E
S
D
T
E
E
D
I
A
Dog
Lupus familis
XP_853317
402
45887
S381
G
D
L
R
N
C
E
S
D
T
E
E
D
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDF3
370
42760
S349
E
D
L
R
N
C
E
S
D
T
E
E
N
I
A
Rat
Rattus norvegicus
O88764
448
51431
N413
R
R
L
C
R
L
E
N
R
Y
D
A
L
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517613
524
60252
E487
K
R
G
F
G
R
L
E
N
R
F
E
A
L
A
Chicken
Gallus gallus
NP_001026784
974
109076
G644
E
A
L
T
S
Q
D
G
K
T
A
E
D
L
A
Frog
Xenopus laevis
NP_001084771
1427
160123
T1071
E
D
I
Q
R
L
V
T
D
S
D
V
D
E
L
Zebra Danio
Brachydanio rerio
NP_001093460
1439
159594
G445
L
D
I
Q
D
K
S
G
E
T
A
L
H
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0KHT7
784
85666
T446
K
E
N
T
Y
T
A
T
F
V
K
K
P
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWL2
534
60474
T506
E
V
I
N
D
V
D
T
D
N
D
G
R
I
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
98.9
89.3
N.A.
97.3
55.1
N.A.
48
28.3
20.5
20.2
N.A.
20
N.A.
N.A.
N.A.
Protein Similarity:
100
73.2
99.4
90.3
N.A.
98.1
68.5
N.A.
57.8
34.3
23.7
23.6
N.A.
32
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
20
N.A.
13.3
40
26.6
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
33.3
60
60
53.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
0
0
0
17
9
9
9
84
% A
% Cys:
0
0
0
9
0
42
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
0
0
17
0
17
0
59
0
25
0
50
0
0
% D
% Glu:
59
9
0
0
0
0
50
9
9
0
42
59
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
9
0
9
0
9
0
0
17
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
25
0
0
0
0
0
0
0
0
0
0
50
0
% I
% Lys:
17
0
0
0
0
9
0
0
9
0
9
9
0
0
0
% K
% Leu:
9
0
59
0
0
17
9
0
0
0
0
9
9
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
42
0
0
9
9
9
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
17
0
42
17
9
0
0
9
9
0
0
9
0
0
% R
% Ser:
0
0
0
0
9
0
9
42
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
17
0
9
0
25
0
59
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
9
0
0
9
0
9
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _