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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF25 All Species: 9.39
Human Site: Y64 Identified Species: 29.52
UniProt: Q9UIL4 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIL4 NP_005346.3 384 40686 Y64 Y N V C V M A Y G Q T G S G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085776 601 65370 Y281 Y N V C V M A Y G Q T G S G K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O35231 824 92538 E167 A Q P V V P C E G C E H S Q E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK6 797 86563 Y109 Y N C S V F A Y G A T G A G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20480 700 77455 S120 P S L P S I P S K V S R L G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P45962 598 67305 R224 F F R V L I E R Y K A E M E K
Sea Urchin Strong. purpuratus XP_786670 361 39722 G64 G K T H T M L G G R Y T Q G L
Poplar Tree Populus trichocarpa XP_002319271 752 84690 L130 L N L I I V E L R K S L A S L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 58.2 N.A. N.A. 21.3 N.A. N.A. N.A. 20.7 N.A. N.A. N.A. 20.1 N.A. 21.5 47.6
Protein Similarity: 100 N.A. 60 N.A. N.A. 32 N.A. N.A. N.A. 30.8 N.A. N.A. N.A. 32.5 N.A. 37.6 62.7
P-Site Identity: 100 N.A. 100 N.A. N.A. 20 N.A. N.A. N.A. 66.6 N.A. N.A. N.A. 6.6 N.A. 6.6 20
P-Site Similarity: 100 N.A. 100 N.A. N.A. 26.6 N.A. N.A. N.A. 73.3 N.A. N.A. N.A. 33.3 N.A. 33.3 26.6
Percent
Protein Identity: 20.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 32.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 46.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 38 0 0 13 13 0 25 0 0 % A
% Cys: 0 0 13 25 0 0 13 0 0 13 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 25 13 0 0 13 13 0 13 13 % E
% Phe: 13 13 0 0 0 13 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 0 0 0 0 13 63 0 0 38 0 63 13 % G
% His: 0 0 0 13 0 0 0 0 0 0 0 13 0 0 0 % H
% Ile: 0 0 0 13 13 25 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 13 0 0 0 0 0 0 13 25 0 0 0 0 50 % K
% Leu: 13 0 25 0 13 0 13 13 0 0 0 13 13 0 25 % L
% Met: 0 0 0 0 0 38 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 0 13 13 0 13 13 0 0 0 0 0 0 0 0 % P
% Gln: 0 13 0 0 0 0 0 0 0 25 0 0 13 13 0 % Q
% Arg: 0 0 13 0 0 0 0 13 13 13 0 13 0 0 0 % R
% Ser: 0 13 0 13 13 0 0 13 0 0 25 0 38 13 0 % S
% Thr: 0 0 13 0 13 0 0 0 0 0 38 13 0 0 0 % T
% Val: 0 0 25 25 50 13 0 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 38 0 0 0 0 0 0 38 13 0 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _