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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBPL All Species: 21.82
Human Site: S166 Identified Species: 48
UniProt: Q9UIM3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIM3 NP_071393.2 349 38176 S166 L I E K C L E S M C Q G E E A
Chimpanzee Pan troglodytes XP_001162594 349 38172 S166 L I E K C L E S M C Q G E E A
Rhesus Macaque Macaca mulatta XP_001114275 349 38055 S166 L I E K C L E S M C Q G E E A
Dog Lupus familis XP_538845 349 38131 S166 L I E K C L E S M C Q G E E A
Cat Felis silvestris
Mouse Mus musculus O35450 347 38283 S164 L M E K C L E S M R Q G E E A
Rat Rattus norvegicus Q6MG81 347 37942 S164 L T E K C L E S M R Q G E E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001084916 447 50310 G222 L Y L K P K Y G F S M T G S E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 A208 I K I Q A K Y A F G A K G N E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301809 575 64059 G358 I A P E Y A F G S S E S Q Q E
Maize Zea mays NP_001149790 553 61673 G359 I P P E Y A F G S T E S K Q D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 G356 I D P E Y A F G S N E S Q Q E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.9 83.6 N.A. 73.3 75.9 N.A. N.A. N.A. 23.4 N.A. N.A. 20.7 N.A. N.A. N.A.
Protein Similarity: 100 100 97.4 89.1 N.A. 84.2 84.2 N.A. N.A. N.A. 40.2 N.A. N.A. 36.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. N.A. 13.3 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. N.A. 13.3 N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: 24 23.5 N.A. 22.8 N.A. N.A.
Protein Similarity: 36.1 37 N.A. 35.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 33.3 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 28 0 10 0 0 10 0 0 0 55 % A
% Cys: 0 0 0 0 55 0 0 0 0 37 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 55 28 0 0 55 0 0 0 28 0 55 55 37 % E
% Phe: 0 0 0 0 0 0 28 0 19 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 37 0 10 0 55 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 37 37 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 64 0 19 0 0 0 0 0 10 10 0 0 % K
% Leu: 64 0 10 0 0 55 0 0 0 0 0 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 55 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % N
% Pro: 0 10 28 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 55 0 19 28 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 55 28 19 0 28 0 10 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 28 0 19 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _