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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBPL All Species: 29.09
Human Site: S191 Identified Species: 64
UniProt: Q9UIM3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIM3 NP_071393.2 349 38176 S191 P V R L T L A S F T Q G R D S
Chimpanzee Pan troglodytes XP_001162594 349 38172 S191 P V R L T L A S F T Q G R D S
Rhesus Macaque Macaca mulatta XP_001114275 349 38055 S191 P V R L T L A S F T Q G R D S
Dog Lupus familis XP_538845 349 38131 S191 P F R L T L A S F T Q G R D S
Cat Felis silvestris
Mouse Mus musculus O35450 347 38283 S189 L A K L R L D S F T N G R D S
Rat Rattus norvegicus Q6MG81 347 37942 S189 L A K L R L D S F T N G R D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001084916 447 50310 S247 Q Y D I R L K S F E K A K E S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 D233 E Y T V K L V D C G K G L E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301809 575 64059 S383 C Y E I E L V S F D K E K E S
Maize Zea mays NP_001149790 553 61673 S384 I Y E V E L I S F V K D K E S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 T381 T Y E V D L L T F D K E R E S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.9 83.6 N.A. 73.3 75.9 N.A. N.A. N.A. 23.4 N.A. N.A. 20.7 N.A. N.A. N.A.
Protein Similarity: 100 100 97.4 89.1 N.A. 84.2 84.2 N.A. N.A. N.A. 40.2 N.A. N.A. 36.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 60 60 N.A. N.A. N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 66.6 66.6 N.A. N.A. N.A. 53.3 N.A. N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: 24 23.5 N.A. 22.8 N.A. N.A.
Protein Similarity: 36.1 37 N.A. 35.7 N.A. N.A.
P-Site Identity: 26.6 26.6 N.A. 26.6 N.A. N.A.
P-Site Similarity: 53.3 53.3 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 0 37 0 0 0 0 10 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 10 0 19 10 0 19 0 10 0 55 0 % D
% Glu: 10 0 28 0 19 0 0 0 0 10 0 19 0 46 10 % E
% Phe: 0 10 0 0 0 0 0 0 91 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 64 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 19 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 19 0 10 0 10 0 0 0 46 0 28 0 0 % K
% Leu: 19 0 0 55 0 100 10 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % N
% Pro: 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % Q
% Arg: 0 0 37 0 28 0 0 0 0 0 0 0 64 0 0 % R
% Ser: 0 0 0 0 0 0 0 82 0 0 0 0 0 0 91 % S
% Thr: 10 0 10 0 37 0 0 10 0 55 0 0 0 0 0 % T
% Val: 0 28 0 28 0 0 19 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _