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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBPL
All Species:
13.33
Human Site:
S204
Identified Species:
29.33
UniProt:
Q9UIM3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UIM3
NP_071393.2
349
38176
S204
D
S
W
E
L
E
T
S
E
K
E
A
L
A
R
Chimpanzee
Pan troglodytes
XP_001162594
349
38172
S204
D
S
W
E
L
E
T
S
E
K
E
A
L
A
R
Rhesus Macaque
Macaca mulatta
XP_001114275
349
38055
S204
D
S
W
E
L
E
T
S
E
K
E
A
L
A
R
Dog
Lupus familis
XP_538845
349
38131
S204
D
S
W
E
L
E
A
S
E
K
E
A
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
O35450
347
38283
M202
D
S
W
E
M
E
A
M
E
K
E
A
L
A
K
Rat
Rattus norvegicus
Q6MG81
347
37942
V202
D
S
W
E
L
E
A
V
E
K
E
A
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084916
447
50310
E260
E
S
W
E
M
N
A
E
E
K
L
E
Q
G
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
E246
E
E
W
K
L
S
D
E
E
R
L
A
E
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301809
575
64059
D396
E
S
W
D
M
N
T
D
E
K
I
E
A
A
G
Maize
Zea mays
NP_001149790
553
61673
E397
E
S
W
D
L
N
N
E
E
K
I
E
A
A
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
E394
E
S
W
D
M
N
T
E
E
K
I
E
A
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.9
83.6
N.A.
73.3
75.9
N.A.
N.A.
N.A.
23.4
N.A.
N.A.
20.7
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.4
89.1
N.A.
84.2
84.2
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
36.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
80
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
24
23.5
N.A.
22.8
N.A.
N.A.
Protein Similarity:
36.1
37
N.A.
35.7
N.A.
N.A.
P-Site Identity:
40
40
N.A.
40
N.A.
N.A.
P-Site Similarity:
60
53.3
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
37
0
0
0
0
64
28
91
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
55
0
0
28
0
0
10
10
0
0
0
0
0
0
0
% D
% Glu:
46
10
0
64
0
55
0
37
100
0
55
37
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
91
0
0
0
0
37
% K
% Leu:
0
0
0
0
64
0
0
0
0
0
19
0
55
0
0
% L
% Met:
0
0
0
0
37
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
37
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
28
% R
% Ser:
0
91
0
0
0
10
0
37
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _