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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBPL All Species: 12.73
Human Site: S80 Identified Species: 28
UniProt: Q9UIM3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIM3 NP_071393.2 349 38176 S80 L E G D S H K S H G S T S Q M
Chimpanzee Pan troglodytes XP_001162594 349 38172 S80 L E G D S H K S H G S T S Q M
Rhesus Macaque Macaca mulatta XP_001114275 349 38055 S80 L E G D S H K S H G S T S Q M
Dog Lupus familis XP_538845 349 38131 S80 L E G D S V K S P G S T S G M
Cat Felis silvestris
Mouse Mus musculus O35450 347 38283 Q79 E G D S D Q F Q V S T N E M A
Rat Rattus norvegicus Q6MG81 347 37942 H79 E G D S D K F H I S T D E M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001084916 447 50310 Q140 F Q G E D L S Q D E D G G I I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 P126 W K G E D L S P N Q D G S I D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301809 575 64059 V270 A W K T V T E V T D D K K V I
Maize Zea mays NP_001149790 553 61673 F210 F T V K D G Y F C P A L A K A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 K159 K D G G V F K K I L A V G E K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.9 83.6 N.A. 73.3 75.9 N.A. N.A. N.A. 23.4 N.A. N.A. 20.7 N.A. N.A. N.A.
Protein Similarity: 100 100 97.4 89.1 N.A. 84.2 84.2 N.A. N.A. N.A. 40.2 N.A. N.A. 36.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 0 0 N.A. N.A. N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 6.6 6.6 N.A. N.A. N.A. 26.6 N.A. N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: 24 23.5 N.A. 22.8 N.A. N.A.
Protein Similarity: 36.1 37 N.A. 35.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 13.3 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 19 0 10 0 28 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 10 19 37 46 0 0 0 10 10 28 10 0 0 10 % D
% Glu: 19 37 0 19 0 0 10 0 0 10 0 0 19 10 0 % E
% Phe: 19 0 0 0 0 10 19 10 0 0 0 0 0 0 0 % F
% Gly: 0 19 64 10 0 10 0 0 0 37 0 19 19 10 0 % G
% His: 0 0 0 0 0 28 0 10 28 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 19 0 0 0 0 19 19 % I
% Lys: 10 10 10 10 0 10 46 10 0 0 0 10 10 10 10 % K
% Leu: 37 0 0 0 0 19 0 0 0 10 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 37 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 10 10 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 10 0 19 0 10 0 0 0 28 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 19 37 0 19 37 0 19 37 0 46 0 0 % S
% Thr: 0 10 0 10 0 10 0 0 10 0 19 37 0 0 0 % T
% Val: 0 0 10 0 19 10 0 10 10 0 0 10 0 10 0 % V
% Trp: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _