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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBPL
All Species:
26.06
Human Site:
T218
Identified Species:
57.33
UniProt:
Q9UIM3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UIM3
NP_071393.2
349
38176
T218
R
E
E
R
A
R
G
T
E
L
F
R
A
G
N
Chimpanzee
Pan troglodytes
XP_001162594
349
38172
T218
R
E
E
R
A
R
G
T
E
L
F
R
A
G
N
Rhesus Macaque
Macaca mulatta
XP_001114275
349
38055
T218
R
E
E
R
A
R
G
T
E
L
F
R
A
G
N
Dog
Lupus familis
XP_538845
349
38131
T218
K
K
E
R
T
R
G
T
E
L
F
R
A
G
N
Cat
Felis silvestris
Mouse
Mus musculus
O35450
347
38283
T216
K
E
E
H
R
R
G
T
E
L
F
R
A
G
N
Rat
Rattus norvegicus
Q6MG81
347
37942
T216
K
E
E
H
R
R
G
T
E
L
F
R
A
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084916
447
50310
T274
C
L
V
K
E
R
G
T
Q
Y
F
K
D
G
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
T260
K
V
Y
K
E
K
G
T
N
Y
F
K
K
E
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301809
575
64059
N410
G
K
K
K
E
E
G
N
V
L
F
K
A
G
K
Maize
Zea mays
NP_001149790
553
61673
N411
G
K
K
K
E
E
G
N
A
L
F
K
S
G
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
N408
S
K
K
K
E
E
G
N
S
K
F
K
G
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.9
83.6
N.A.
73.3
75.9
N.A.
N.A.
N.A.
23.4
N.A.
N.A.
20.7
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.4
89.1
N.A.
84.2
84.2
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
36.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
24
23.5
N.A.
22.8
N.A.
N.A.
Protein Similarity:
36.1
37
N.A.
35.7
N.A.
N.A.
P-Site Identity:
33.3
26.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
60
60
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
0
0
0
10
0
0
0
64
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
46
55
0
46
28
0
0
55
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% F
% Gly:
19
0
0
0
0
0
100
0
0
0
0
0
10
91
0
% G
% His:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
37
37
28
46
0
10
0
0
0
10
0
46
10
0
28
% K
% Leu:
0
10
0
0
0
0
0
0
0
73
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
28
10
0
0
0
0
0
64
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
28
0
0
37
19
64
0
0
0
0
0
55
0
0
10
% R
% Ser:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
10
0
0
73
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _